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绿纹玉斑蛇毒液:与出血综合征相关的体内作用和分子方面。

Lonomia obliqua venom: In vivo effects and molecular aspects associated with the hemorrhagic syndrome.

机构信息

Laboratório de Bioquímica Farmacológica, Centro de Biotecnologia (UFRGS), Av. Bento Gonçalves, 9500, CEP 91501-970, Porto Alegre, RS, Brazil.

出版信息

Toxicon. 2010 Dec 15;56(7):1103-12. doi: 10.1016/j.toxicon.2010.01.013. Epub 2010 Jan 28.

Abstract

Caterpillar envenomation has been an emergent health issue. Lonomia obliqua is a medically important animal that causes a hemorrhagic syndrome that can progress to acute renal failure, intracranial hemorrhage and death. In the past few years the molecular characterization of L. obliqua venom in addition to experimental models has provided fundamental information to the understanding of the envenomation syndrome. Herein studies from several authors which characterized the complex toxic-pharmacological actions of whole venom are reviewed.

摘要

毛毛虫螫伤已成为一个紧急的健康问题。绿长角天牛是一种医学上重要的动物,它会引起出血综合征,可进展为急性肾衰竭、颅内出血和死亡。在过去的几年中,绿长角天牛毒液的分子特征以及实验模型为理解螫伤综合征提供了基础信息。在此,综述了几位作者对全毒液的复杂毒理药理学作用进行的研究。

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