Mokranjac Dejana, Neupert Walter
Institute for Physiological Chemistry and Munich Center for Integrated Protein Science CIPSM, Ludwig-Maximilians University, Butenandtstr. 5, 81377 Munich, Germany.
Biochim Biophys Acta. 2010 Jun-Jul;1797(6-7):1045-54. doi: 10.1016/j.bbabio.2010.01.026. Epub 2010 Jan 28.
The TIM23 complex in the inner membrane of mitochondria mediates import of essentially all matrix proteins and a large number of inner membrane proteins. Here we present an overview on the latest insights into the structure and function of this remarkable molecular machine.
线粒体内膜中的TIM23复合物介导了基本上所有基质蛋白和大量内膜蛋白的导入。在此,我们概述了对这一非凡分子机器的结构和功能的最新见解。