Demarquay J-F, Perrin H, Hastier P, Higuero T, Ferrari C, Rampal P, Dumas R
Service d'Hépatogastro-Entérologie du Centre Hospitalier Princesse-Grace, Principauté de Monaco, avenue Pasteur, 98012 Monaco cedex, France.
Gastroenterol Clin Biol. 2010 Feb;34(2):150-3. doi: 10.1016/j.gcb.2009.09.006. Epub 2010 Feb 8.
Perforation of the colon during colonoscopy is still one of the most severe complications of this technique and occurs with a frequency of between 0.12 % and 0.2 % of cases after diagnostic colonoscopy and in up to 3 % of patients after therapeutic colonoscopy. The site of perforation is usually the sigmoid colon. The gold standard for treatment of this complication is surgery to be performed as rapidly as possible: a simple suture and peritoneal cleaning, with limited resection and anastomosis or colostomy only in case of confirmed fecal peritonitis. However, interventional endoscopy has made progress, in particular endoscopic suturing and Natural Orifice Transluminal Endocopic Surgery (NOTES) has been developed. There are several reports of endoscopically sutured perforated colons, most less than 10mm. We report our experience of two colonic perforations which were at least 10mm treated by endoscopic suturing with hemoclips: a perforated sigmoid diverticulum during simple colonoscopy in the first case and a large polypectomy by endoscopic mucosal resection of the ascending colon in the second.
结肠镜检查期间结肠穿孔仍然是该技术最严重的并发症之一,在诊断性结肠镜检查后发生率为0.12%至0.2%,在治疗性结肠镜检查后高达3%的患者中发生。穿孔部位通常是乙状结肠。治疗该并发症的金标准是尽快进行手术:简单缝合和腹膜清理,仅在确诊为粪性腹膜炎时进行有限切除和吻合或结肠造口术。然而,介入性内镜检查取得了进展,特别是内镜缝合技术得到了发展,自然腔道内镜手术(NOTES)也已出现。有几篇关于内镜缝合结肠穿孔的报道,大多数穿孔小于10毫米。我们报告了两例至少10毫米的结肠穿孔经内镜用止血夹缝合治疗的经验:第一例是在简单结肠镜检查期间乙状结肠憩室穿孔,第二例是升结肠内镜黏膜下切除术切除大息肉后穿孔。