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超声引导高强度聚焦超声治疗腹壁子宫内膜异位症:初步结果。

Ultrasound-guided high-intensity focused ultrasound treatment for abdominal wall endometriosis: preliminary results.

机构信息

Department of Ultrasound, Chinese PLA General Hospital, 28 Fuxing Road, Beijing 100853, China.

出版信息

Eur J Radiol. 2011 Jul;79(1):56-9. doi: 10.1016/j.ejrad.2009.12.034. Epub 2010 Feb 8.

Abstract

PURPOSE

To evaluate the safety and therapeutic efficacy of ultrasound (US)-guided high-intensity focused ultrasound (HIFU) ablation for the treatment of abdominal wall endometriosis (AWE).

MATERIALS AND METHODS

Twenty-one consecutive patients with AWE were treated as outpatients by US-guided HIFU ablation under conscious sedation. The median size of the AWE was 2.4 cm (range 1.0-5.3 cm). An acoustic power of 200-420 W was used, intermittent HIFU exposure of 1s was applied. Treatment was considered complete when the entire nodule and its nearby 1cm margin become hyperechoic on US. Pain relief after HIFU ablation was observed and the treated nodule received serial US examinations during follow-up.

RESULTS

All AWE was successfully ablated after one session of HIFU ablation, the ablation time lasted for 5-48 min (median 13 min), no major complications occurred. The cyclic pain disappeared in all patients during a mean follow-up of 18.7 months (range 3-31 months). The treated nodules gradually shank over time, 16 nodules became unnoticeable on US during follow-up.

CONCLUSION

US-guided HIFU ablation appears to be safe and effective for the treatment of AWE.

摘要

目的

评估超声(US)引导高强度聚焦超声(HIFU)消融治疗腹壁子宫内膜异位症(AWE)的安全性和疗效。

材料与方法

21 例 AWE 患者在清醒镇静下接受 US 引导 HIFU 消融治疗。AWE 的中位大小为 2.4cm(范围 1.0-5.3cm)。采用 200-420W 的声功率,间歇性 HIFU 暴露 1s。当整个结节及其附近 1cm 边缘在 US 上均呈高回声时,认为治疗完成。观察 HIFU 消融后的疼痛缓解情况,并在随访期间对治疗结节进行连续 US 检查。

结果

所有 AWE 均在单次 HIFU 消融后成功消融,消融时间为 5-48min(中位 13min),无重大并发症发生。在平均 18.7 个月(范围 3-31 个月)的随访中,所有患者的周期性疼痛均消失。治疗结节随时间逐渐缩小,16 个结节在随访中超声检查不可见。

结论

US 引导 HIFU 消融治疗 AWE 安全有效。

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