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超声引导高强度聚焦超声治疗腹壁子宫内膜异位症:一项回顾性研究。

Ultrasound-guided high-intensity focused ultrasound treatment for abdominal wall endometriosis: a retrospective study.

机构信息

Department of Obstetrics and Gynaecology, Suining Central Hospital, Sichuan, China.

出版信息

BJOG. 2017 Aug;124 Suppl 3:59-63. doi: 10.1111/1471-0528.14741.

Abstract

OBJECTIVE

To evaluate the safety and efficacy of ultrasound-guided high-intensity focused ultrasound (USgHIFU) for treating abdominal wall endometrioses (AWE).

DESIGN

A retrospective study.

SETTING

Department of Obstetrics and Gynaecology in China.

POPULATION

Patients with abdominal wall endometriosis.

METHODS

From August 2010 to April 2014, 32 patients with AWE were treated with USgHIFU in our hospital. USgHIFU treatment was performed with the Model JC-200 High Intensity Focused Ultrasound Tumor Therapeutic System. The symptom relief and the adverse effects were evaluated after USgHIFU ablation.

MAIN OUTCOME MEASURES

USgHIFU as a new treatment option for patients with AWE.

RESULTS

Contrast-enhanced ultrasound showed that all lesions were successfully ablated with USgHIFU. The follow-up results showed that the average volume of AWE lesions at 6 months after USgHIFU was significantly smaller than that before treatment (2.80 ± 0.12 versus 1.33 ± 0.31 cm ). The pain scores at 6 months after treatment were significantly lower than those before treatment (6.80 ± 2.64 versus 1.80 ± 0.3). The non-perfused volume (indicative of successful ablation) was measured in all patients immediately after treatment, ranging from 0.9 to 2.1 cm (median: 1.6 cm ), and the fractional ablation ranged from 87% to 100% (median: 94%). Local oedema was observed in these patients, lasting for 1-3 days only. No severe complications occurred during the follow-up period.

CONCLUSIONS

Based on our study, USgHIFU ablation is a safe and effective method for treating AWE.

TWEETABLE ABSTRACT

As a non-invasive treatment technique, HIFU could be used to treat abdominal wall endometriosis.

摘要

目的

评估超声引导高强度聚焦超声(USgHIFU)治疗腹壁子宫内膜异位症(AWE)的安全性和有效性。

设计

回顾性研究。

地点

中国妇产科。

人群

腹壁子宫内膜异位症患者。

方法

2010 年 8 月至 2014 年 4 月,我院 32 例 AWE 患者接受 USgHIFU 治疗。采用 JC-200 高强度聚焦超声肿瘤治疗系统进行 USgHIFU 治疗。消融后评估症状缓解和不良反应。

主要观察指标

USgHIFU 作为 AWE 患者的一种新治疗选择。

结果

增强超声显示所有病变均成功消融。随访结果显示,USgHIFU 治疗 6 个月后 AWE 病变的平均体积明显小于治疗前(2.80±0.12cm 比 1.33±0.31cm)。治疗后 6 个月疼痛评分明显低于治疗前(6.80±2.64 比 1.80±0.3)。所有患者治疗后即刻测量无灌注体积(提示成功消融),范围为 0.9-2.1cm(中位数:1.6cm),消融分数为 87%-100%(中位数:94%)。这些患者观察到局部水肿,仅持续 1-3 天。随访期间无严重并发症发生。

结论

根据我们的研究,USgHIFU 消融是治疗 AWE 的一种安全有效的方法。

推文摘要

作为一种非侵入性治疗技术,HIFU 可用于治疗腹壁子宫内膜异位症。

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