Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, CA 95616, USA.
Vet Clin North Am Food Anim Pract. 2010 Mar;26(1):73-8, table of contents. doi: 10.1016/j.cvfa.2009.10.002.
Moraxella bovoculi is a recently described gram-negative coccus that was isolated from eyes of calves with infectious bovine keratoconjunctivitis (IBK, or "pinkeye") in 2002. This organism probably has been associated with IBK for many years and, until it was shown to be distinct from M ovis, may have been incorrectly identified as M ovis, Branhamella ovis, M ovis-like, or B ovis-like by diagnostic laboratories. M bovoculi can be isolated from normal calves and cattle with IBK or conjunctivitis. An exact role for M bovoculi in the pathogenesis of IBK is uncertain; however, anecdotal evidence of autogenous M bovoculi bacterins successfully preventing IBK suggests that it may play a role in IBK pathogenesis. Developers of vaccines against IBK should consider including M bovoculi antigens in vaccines to prevent IBK.
牛莫拉菌是一种最近被描述的革兰氏阴性球菌，于 2002 年从患有传染性牛角膜结膜炎（IBK，又称“红眼病”）的犊牛眼睛中分离出来。该病原体可能与 IBK 相关多年，并且在被证明与莫氏菌不同之前，它可能一直被诊断实验室错误地鉴定为莫氏菌、绵羊布兰汉氏菌、莫氏菌样或牛氏菌样。牛莫拉菌可从正常犊牛和患有 IBK 或结膜炎的牛中分离出来。牛莫拉菌在 IBK 发病机制中的确切作用尚不确定；然而，有传闻证据表明，源自牛莫拉菌的菌苗成功预防了 IBK，这表明它可能在 IBK 的发病机制中发挥作用。IBK 疫苗的开发者应考虑在疫苗中加入牛莫拉菌抗原，以预防 IBK。
