Orthopedic Specialists of Louisiana, Shreveport, Louisiana 71101, USA.
Arthroscopy. 2010 Jan;26(1):105-11. doi: 10.1016/j.arthro.2009.05.009. Epub 2009 Nov 25.
Viscosupplementation is defined as the use of intra-articular hyaluronan therapy for symptomatic osteoarthritis (OA). Originally used for the treatment of ophthalmic disorders, viscosupplementation has been available for over a decade in the United States for the treatment of pain secondary to OA of the knee in patients who have not responded adequately to conservative oral pharmaceuticals including nonsteroidal anti-inflammatories and simple analgesics. The majority of patients with symptomatic knee OA will have evidence of meniscal and/or articular surface pathology, and most orthopaedic surgeons include arthroscopic surgery as a possible treatment modality for the symptomatic patient. Although arthroscopic meniscectomy is the most commonly performed orthopaedic procedure in the United States, in patients with concomitant OA, disease-related pain can persist after arthroscopic surgery. This article reviews some of the more recent evidence recommending the use of viscosupplementation for the management of symptomatic knee OA and pain relief after arthroscopy.
黏弹性补充疗法被定义为关节内透明质酸治疗用于治疗症状性骨关节炎（OA）。最初用于治疗眼科疾病，黏弹性补充疗法在美国已经使用了十多年，用于治疗对包括非甾体抗炎药和简单镇痛药在内的保守口服药物治疗反应不足的膝骨关节炎患者的疼痛。大多数有症状的膝骨关节炎患者都会有半月板和/或关节表面病理的证据，大多数骨科医生将关节镜手术作为有症状患者的一种可能的治疗方式。虽然关节镜下半月板切除术是美国最常进行的骨科手术，但对于同时患有 OA 的患者，关节镜手术后疾病相关的疼痛可能仍然存在。本文回顾了一些最近的证据，推荐使用黏弹性补充疗法来管理症状性膝骨关节炎和关节镜手术后的疼痛缓解。
