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关节镜下部分半月板切除术 后关节内注射黏弹性补充剂的疗效:一项随机对照试验。

The efficacy of intraarticular viscosupplementation after arthroscopic partial meniscectomy: a randomized controlled trial.

机构信息

Department of Orthopaedic Surgery, Kyung Hee University Hospital, Seoul, Republic of Korea.

Department of Orthopaedic Surgery, Uijeongbu Eulji Medical Center, Eulji University School of Medicine, 712, Dongil-ro, Uijeongbu-si, Gyeonggi-do, Republic of Korea.

出版信息

BMC Musculoskelet Disord. 2022 Jan 4;23(1):32. doi: 10.1186/s12891-021-04990-3.

Abstract

BACKGROUND

This study aimed to evaluate the efficacy of viscosupplementation after arthroscopic partial meniscectomy.

METHOD

A randomized controlled trial of 47 patients who underwent arthroscopic partial meniscectomy was conducted between March 2020 and March 2021. Patients were randomized into two groups: a viscosupplementation group (n = 23) and a control group (n = 24). A single-dose intraarticular hyaluronic acid injection was used as viscosupplementation. The 100 mm visual analogue scale (VAS) for pain assessment was measured at baseline and at 1 day, 2 weeks, 6 weeks, and 3 months post-surgery. The International Knee Documentation Committee (IKDC), Tegner, Lysholm, and Western Ontario and McMaster University Osteoarthritis Index (WOMAC) scores and range of motion (ROM) of the knee were measured at baseline, 2 weeks, 6 weeks, and 3 months.

RESULTS

The 100 mm VAS score for pain was significantly lower in the viscosupplementation group at 2 weeks post-surgery (27.5 mm vs. 40.7 mm, P = 0.047). ROM was significantly greater in the viscosupplementation group than in the control group at 2 weeks (131.5° vs. 121.0°, P = 0.044) post-surgery. No significant differences were observed in the IKDC or in the Tegner, Lysholm, and WOMAC scores between the two groups.

CONCLUSIONS

Viscosupplementation after arthroscopic partial meniscectomy significantly reduced pain at 2 weeks post-surgery and improved ROM of the knee at 2 weeks post-surgery. There might be some benefits in terms of pain and functional recovery of viscosupplementation after arthroscopic surgery.

STUDY DESIGN

Randomized controlled trial; Level of evidence, 1.

TRIAL REGISTRATION

This randomized controlled trial was registered at cris.nih.go.kr # KCT0004921 .

摘要

背景

本研究旨在评估关节镜下部分半月板切除术 后 黏弹性补充治疗的疗效。

方法

2020 年 3 月至 2021 年 3 月期间进行了一项随机对照试验,纳入了 47 例行关节镜下部分半月板切除术的患者。患者被随机分为两组:黏弹性补充治疗组(n=23)和对照组(n=24)。采用单次关节内透明质酸注射作为黏弹性补充治疗。使用 100mm 视觉模拟评分(VAS)评估疼痛,分别在基线时和术后 1 天、2 周、6 周和 3 个月时进行测量。在基线时、术后 2 周、6 周和 3 个月时测量国际膝关节文献委员会(IKDC)、Tegner、Lysholm 和西安大略和麦克马斯特大学骨关节炎指数(WOMAC)评分以及膝关节活动度(ROM)。

结果

术后 2 周时,黏弹性补充治疗组的疼痛 VAS 评分显著低于对照组(27.5mm 比 40.7mm,P=0.047)。术后 2 周时,黏弹性补充治疗组的 ROM 显著大于对照组(131.5°比 121.0°,P=0.044)。两组间 IKDC 评分以及 Tegner、Lysholm 和 WOMAC 评分无显著差异。

结论

关节镜下部分半月板切除术后黏弹性补充治疗可显著减轻术后 2 周时的疼痛,并改善术后 2 周时的膝关节 ROM。关节镜手术后黏弹性补充治疗在疼痛和功能恢复方面可能具有一定优势。

研究设计

随机对照试验;证据等级,1 级。

试验注册

本随机对照试验在 cris.nih.go.kr # KCT0004921 注册。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/23d5/8729128/661b4631601a/12891_2021_4990_Fig1_HTML.jpg

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