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加速白内障手术后视力改善和跌倒减少的系统评价和荟萃分析。

Vision improvement and reduction in falls after expedited cataract surgery Systematic review and metaanalysis.

机构信息

British Columbia Injury Research and Prevention Unit, Department of Paediatrics, BC Children's Hospital, Vancouver, Canada.

出版信息

J Cataract Refract Surg. 2010 Jan;36(1):13-9. doi: 10.1016/j.jcrs.2009.07.032.

Abstract

PURPOSE

To quantify the benefits of expedited cataract surgery in improving visual acuity and reducing fall-related injuries in the older population.

SETTING

Developmental Neurosciences and Child Health: Neurons to Neighbourhoods, Vancouver, British Columbia, Canada.

METHODS

A systematic review of the literature was conducted. Studies were included if expedited cataract surgery was presented as a measure to enhance vision and to reduce injury. Published and unpublished studies with any type of study design were included. Studies were identified from 12 databases including Medline (1950 to 2008) and Embase (1980 to 2008). The metaanalysis was specific to randomized controlled trials (RCTs).

RESULTS

The review comprised 737 participants. Sufficient data for the metaanalysis were available to evaluate the impact of expedited cataract surgery on improved visual acuity and a reduced fall rate. Twenty-two publications that included RCTs and prospective cohort studies met the inclusion criteria. Three studies evaluated visual acuity after expedited routine cataract surgery and routine cataract surgery. The pooled estimate showed that expedited cataract surgery increased visual acuity by more than 7 times (odds ratio [OR], 7.22; 95% confidence interval [CI], 3.16-16.55; P<.0001). Pooling of data from 2 RCTs of 535 participants showed a nonsignificant reduction in the incidence of falls after expedited cataract surgery (OR, 0.81; 95% CI, 0.55-1.17).

CONCLUSIONS

Accumulating evidence indicates that expedited cataract surgery is effective in significantly enhancing vision but is inconclusive in preventing falls.

FINANCIAL DISCLOSURE

No author has a financial or proprietary interest in any material or method mentioned.

摘要

目的

定量评估加速白内障手术在改善视力和减少老年人跌倒相关伤害方面的益处。

背景

发育神经科学和儿童健康:从神经元到邻里,不列颠哥伦比亚省温哥华。

方法

对文献进行了系统回顾。纳入的研究将加速白内障手术作为提高视力和减少伤害的措施进行了描述。纳入了任何类型研究设计的已发表和未发表的研究。研究从包括 Medline(1950 年至 2008 年)和 Embase(1980 年至 2008 年)在内的 12 个数据库中确定。荟萃分析专门针对随机对照试验(RCT)。

结果

综述包括 737 名参与者。有足够的数据进行荟萃分析,以评估加速白内障手术对提高视力和降低跌倒率的影响。有 22 篇出版物包括 RCT 和前瞻性队列研究,符合纳入标准。三项研究评估了加速常规白内障手术和常规白内障手术后的视力。汇总估计表明,加速白内障手术使视力提高了 7 倍以上(比值比 [OR],7.22;95%置信区间 [CI],3.16-16.55;P<.0001)。对 535 名参与者的 2 项 RCT 数据进行汇总显示,加速白内障手术后跌倒发生率无显著降低(OR,0.81;95%CI,0.55-1.17)。

结论

越来越多的证据表明,加速白内障手术在显著提高视力方面是有效的,但在预防跌倒方面尚无定论。

利益披露

没有作者在提到的任何材料或方法中拥有经济或所有权利益。

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