Halloran Donna R, Swindle Jason, Takemoto Steve K, Schnitzler Mark A
Department of Pediatrics, Saint Louis University, Saint Louis, MO 63104-1095, USA.
Clin Pediatr (Phila). 2010 May;49(5):485-90. doi: 10.1177/0009922809347369. Epub 2010 Jan 28.
To evaluate the prevalence of atypical antipsychotic use in privately insured children and the diagnoses associated with treatment.
Claims were used to conduct a retrospective cohort study of children aged 2 through 18 years in the Midwest, covered by private insurance between 2002 and 2005 (n = 172,766). The 1-year prevalence of children receiving atypical antipsychotics was determined along with associated diagnoses.
The 1-year prevalence of atypical antipsychotics ranged from 7.9 per 1000 in 2002 to 9.0 in 2005. The leading diagnoses were disruptive behavior disorders (67%), mood disorders (65%), and anxiety disorders (43%).The authors found that 75% of children on atypical antipsychotics had more than one psychiatric diagnosis.
Atypical antipsychotic use is primarily seen in children who have multiple psychiatric diagnoses. Studies are needed to assess the long-term safety and effectiveness in such patients with multiple diagnoses.
评估参加私人保险的儿童使用非典型抗精神病药物的流行情况以及与治疗相关的诊断。
利用索赔数据对2002年至2005年期间在中西部地区参加私人保险的2至18岁儿童（n = 172,766）进行回顾性队列研究。确定接受非典型抗精神病药物治疗的儿童的1年患病率以及相关诊断。
非典型抗精神病药物的1年患病率从2002年的每1000人7.9例到2005年的9.0例不等。主要诊断为破坏性行为障碍（67%）、情绪障碍（65%）和焦虑障碍（43%）。作者发现，使用非典型抗精神病药物的儿童中有75%有不止一种精神疾病诊断。
非典型抗精神病药物的使用主要见于有多种精神疾病诊断的儿童。需要开展研究以评估此类有多种诊断的患者的长期安全性和有效性。
