Frank G H, Marshall R G, Smith P C
Am J Vet Res. 1977 Oct;38(10):1497-1502.
Aerosol or intramuscular exposure to infectious bovine rhinotracheitis virus elicited generally comparable levels of serum antibody in cattle, but not measurable nasal secretion antibody. Aerosol-exposed cattle developed signs of mild clinical disease, fever, and leukopenia and shed virus from their nasal passages. Cattle exposed by intra-muscular inoculation developed a brief febrile response and leukopenia but did not shed virus. After an aerosol challenge exposure, cattle in each group developed detectable nasal secretion antibodies, but no clinical signs of disease.
牛经气溶胶或肌肉注射感染牛传染性鼻气管炎病毒后,通常会产生相当水平的血清抗体,但鼻分泌物抗体无法检测到。经气溶胶暴露的牛出现轻度临床疾病、发热和白细胞减少的症状,并从鼻腔排出病毒。经肌肉接种的牛出现短暂的发热反应和白细胞减少,但不排出病毒。在气溶胶攻击暴露后,每组牛都产生了可检测到的鼻分泌物抗体,但没有疾病的临床症状。