Hwang Jiyoung, Chung Myung Jin, Bae Younga, Shin Kyung Min, Jeong Sun Young, Lee Kyung Soo
Department of Radiology, Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, Gangnam-Gu, Seoul, Korea.
J Comput Assist Tomogr. 2010 Jan;34(1):31-4. doi: 10.1097/RCT.0b013e3181b5c630.
To evaluate the relationship between a computed tomographic reconstruction kernel and the sensitivity of a computer-aided detection (CAD) system for lung nodule detection.
We retrospectively studied 36 consecutive patients with no known pulmonary nodules who underwent low-dose computed tomography for lung cancer screening with 3 different reconstruction kernels (B, C, and L). All series were reviewed with a commercial CAD system for lung nodule detection.
The 36 scans showed 231 uncalcified nodules (170 micronodules and 61 nodules). There was little variation of sensitivities for each series (82%, 88%, and 82% for the nodules of B, C, and L, respectively). When the results of 2 series were combined, sensitivities were boosted (B + C, 89%; B + L, 95%; and C + L, 96% for the nodules).
Sensitivity of the CAD system was influenced by the selection of the reconstruction kernel. By combining data from 2 different kernels, CAD sensitivity can be elevated without further patient radiation exposure.
评估计算机断层扫描重建核与计算机辅助检测（CAD）系统对肺结节检测敏感性之间的关系。
我们回顾性研究了36例无已知肺结节的连续患者，这些患者接受了低剂量计算机断层扫描以进行肺癌筛查，扫描采用3种不同的重建核（B、C和L）。所有系列均使用商用CAD系统进行肺结节检测评估。
36次扫描显示出231个未钙化结节（170个微结节和61个结节）。各系列的敏感性差异不大（B、C和L系列结节的敏感性分别为82%、88%和82%）。当将两个系列的结果合并时，敏感性提高（B + C系列结节为89%；B + L系列为95%；C + L系列为96%）。
CAD系统的敏感性受重建核选择的影响。通过合并来自两种不同核的数据，可在不增加患者辐射暴露的情况下提高CAD的敏感性。
