Garbino Jorge, Myers Catherine, Ambrosioni Juan, Gumy-Pause Fabienne
Division of Infectious Diseases, Department of Internal Medicine, University of Geneva Hospitals, Geneva, Switzerland.
J Pediatr Hematol Oncol. 2010 Mar;32(2):85-7. doi: 10.1097/MPH.0b013e3181c2bdce.
Zygomycosis is an emerging, opportunistic fungal infection particularly affecting immunocomprised patients. We report the case of a 10-year-old girl who developed pulmonary zygomycosis because of Cunninghamella bertholletiae 1 year after undergoing bone marrow transplantation complicated with severe cutaneous and digestive graft-versus-host disease. Treatment with surgery and liposomal amphotericin B followed by posaconazole successfully treated the infection.
接合菌病是一种新出现的机会性真菌感染,尤其影响免疫功能低下的患者。我们报告一例10岁女孩的病例,该女孩在接受骨髓移植并发严重皮肤和消化道移植物抗宿主病1年后,因柏氏小克银汉霉感染而发生肺部接合菌病。手术联合脂质体两性霉素B治疗,随后使用泊沙康唑成功治愈了感染。