新型生物活性天然产物的见解：7-异戊烯氧基香豆素

Insights on novel biologically active natural products: 7-isopentenyloxycoumarin.

作者信息

Epifano Francesco, Pelucchini Caroline, Curini Massimo, Genovese Salvatore

机构信息

Dipartimento di Scienze del Farmaco, Università "G. D 'Annunzio" di Chieti-Pescara, Via dei Vestini 31, Chieti Scalo, Italy, 66013.

出版信息

Nat Prod Commun. 2009 Dec;4(12):1755-60.

PMID:20120120

Abstract

7-Isopentenyloxycoumarin is a prenyloxyphenylpropanoid derivative found in low concentration in a restricted number of plant families (Apiaceae, Asteraceae, and Rutaceae). Synthetic schemes were recently developed enabling sufficient quantities of the title coumarin to be obtained in order to evidence its valuable biological effects, mainly as an anti-cancer agent. The aim of this review is to examine the phytochemical and pharmacological properties of this compound.

摘要

7-异戊烯氧基香豆素是一种异戊烯氧基苯基丙烷类衍生物，在少数植物科（伞形科、菊科和芸香科）中含量较低。最近开发了合成方案，能够获得足够量的标题香豆素，以证明其有价值的生物学效应，主要是作为一种抗癌剂。这篇综述的目的是研究该化合物的植物化学和药理学特性。