异维A酸治疗中重度痤疮患者的心理影响。

Psychological impact of isotretinoin treatment in patients with moderate and severe acne.

作者信息

Simić Dubravka, Situm Mirna, Letica Edita, Penavić Jasna Zeljko, Zivković Maja Vurnek, Tomić Teo

机构信息

Department for Dermatology and Venerology, University Clinical Hospital Mostar, Mostar, Bosnia and Herzegovina.

出版信息

Coll Antropol. 2009 Dec;33 Suppl 2:15-9.

PMID:20120397

Abstract

Acne patients are subject to different degree of psychosocial distress. The emotional impact of acne vulgaris due to disfigurement caused by the disease is undisputed. Most common reactions to the acne are depression and anxiety. The use of isotretinoin, one of the most effective options in acne treatment, increases depression symptoms. The aim of this study was to investigate the psychological status of the patients with moderate to severe acne and to compare patients treated with isotretinoin with patients treated with vitamin C. A total of 85 patients suffering from acne vulgaris were included in the study. The results of this study do not find a significant correlation between the use of isotretinoin and the psychological effects of the drug.

摘要

痤疮患者会遭受不同程度的心理社会困扰。寻常痤疮因疾病导致容貌毁损所产生的情感影响是无可争议的。对痤疮最常见的反应是抑郁和焦虑。异维A酸是痤疮治疗中最有效的选择之一，使用它会加重抑郁症状。本研究的目的是调查中度至重度痤疮患者的心理状况，并比较接受异维A酸治疗的患者和接受维生素C治疗的患者。共有85名寻常痤疮患者纳入本研究。本研究结果未发现使用异维A酸与该药物的心理效应之间存在显著相关性。