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2003 - 2005年黑塞哥维那地区类风湿关节炎的患病率及危险因素

Prevalence and risk factors of the rheumatoid arthritis in Herzegovina region in 2003-2005.

作者信息

Damjanović Vesna, Vasilj Ivan, Vlak Tonko, Zelenika Diana

机构信息

School of Medicine, University of Mostar, Mostar, Bosnia and Herzegovina.

出版信息

Coll Antropol. 2009 Dec;33 Suppl 2:73-7.

Abstract

In this study we evidenced prevalence of the rheumatoid arthritis (RA) in Herzegovina region of the Bosnia and Herzegovina and studied selected RA risk factors. Sample of subjects comprised RA diagnosed subjects which were compared to randomly selected controls. In diagnosing the RA we used criteria for the classification of rheumatoid arthritis suggested by The American College of Rheumatology. Risk factors of RA included in this investigation were (1) educational status, (2) quality of nutrition, and (3) socioeconomic status. Average prevalence of the RA in our sample was 0.46/100, ranged from 0.36/100 to 0.64/100, which is comparable to other European samples. The RA occurrence is six times more often in females than in males. We have found indices that the Mediterranean diet has to be considered as protective factor against RA. Although RA occurrence is more frequent in the low socioeconomic samples of subjects, because of the methodological reasons we can not undoubtedly support the socioeconomic status as significant risk factor of the RA. Finally, it is interesting that we have found education level as risk factor significantly related to RA occurrence in our sample. All evidenced should be more precisely studied in some future study, while accurately controlling all relevant factors.

摘要

在本研究中,我们证实了波斯尼亚和黑塞哥维那黑塞哥维那地区类风湿性关节炎(RA)的患病率,并研究了选定的RA风险因素。研究对象样本包括已确诊为RA的受试者,并与随机选择的对照组进行比较。在诊断RA时,我们采用了美国风湿病学会建议的类风湿性关节炎分类标准。本调查纳入的RA风险因素包括:(1)教育程度,(2)营养质量,以及(3)社会经济地位。我们样本中RA的平均患病率为0.46/100,范围在0.36/100至0.64/100之间,这与其他欧洲样本相当。女性患RA的几率是男性的六倍。我们发现有迹象表明地中海饮食应被视为预防RA的保护因素。尽管在社会经济地位较低的受试者样本中RA的发生率更高,但由于方法学原因,我们无法确凿地支持社会经济地位作为RA的重要风险因素。最后,有趣的是,我们发现教育水平是与我们样本中RA发生显著相关的风险因素。所有这些证据都应在未来的一些研究中更精确地进行研究,同时准确控制所有相关因素。

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