Venetsanopoulou Aliki I, Kalpourtzi Natasa, Alamanos Yannis, Gavana Magda, Vantarakis Apostolos, Hadjichristodoulou Christos, Mouchtouri Varvara A, Chlouverakis Grigoris, Trypsianis Grigoris, Drosos Alexandros A, Touloumi Giota, Voulgari Paraskevi V
Department of Rheumatology, School of Health Sciences, Faculty of Medicine, University of Ioannina, 45110, Ioannina, Greece.
Departmentof Hygiene, Epidemiology, and Medical Statistics, Medical School, National and Kapodistrian University of Athens, Athens, Greece.
Rheumatol Int. 2023 Jul;43(7):1349-1355. doi: 10.1007/s00296-023-05316-3. Epub 2023 Mar 31.
Rheumatoid arthritis (RA) is considered the most common form of autoimmune arthritis. The disease's prevalence is around 0.5-1% worldwide, but it seems to vary among different populations. The aim of this study was to estimate the prevalence of self-reported diagnosed RA in the general adult population in Greece. The data were derived from the Greek Health Examination Survey EMENO, a population-based survey performed between 2013 and 2016. Of the 6006 participants (response rate 72%), 5884 were eligible for this study. Prevalence estimates were calculated according to the study design. Prevalence of self-reported RA was estimated to be overall 0.5% (95% CI 0.4-0.7) being approximately three times higher in women than in men (0.7% vs 0.2%, p value = 0.004). A decrease in the prevalence of RA was observed in urban areas of the country. In contrast, higher disease rates were reported in individuals with lower socioeconomic status. Multivariable regression analysis showed that gender, age, and income were related to the occurrence of the disease. Osteoporosis and thyroid disease were the two comorbidities observed at statistically significant higher rates in individuals with self-reported RA. The prevalence of self-reported RA in Greece is similar to that reported in other European countries. Gender, age, and income are the main factors related to the disease's prevalence in Greece.
类风湿关节炎（RA）被认为是自身免疫性关节炎最常见的形式。该疾病在全球的患病率约为0.5%-1%，但在不同人群中似乎有所不同。本研究的目的是估计希腊普通成年人群中自我报告诊断为RA的患病率。数据来自希腊健康检查调查EMENO，这是一项在2013年至2016年期间进行的基于人群的调查。在6006名参与者中（应答率72%），5884名符合本研究条件。根据研究设计计算患病率估计值。自我报告的RA患病率总体估计为0.5%（95%CI 0.4-0.7），女性患病率约为男性的三倍（0.7%对0.2%，p值=0.004）。该国城市地区的RA患病率有所下降。相比之下，社会经济地位较低的个体报告的疾病发生率较高。多变量回归分析表明，性别、年龄和收入与疾病的发生有关。骨质疏松症和甲状腺疾病是自我报告患有RA的个体中观察到的两种合并症，其发生率在统计学上显著更高。希腊自我报告的RA患病率与其他欧洲国家报告的患病率相似。性别、年龄和收入是与希腊该疾病患病率相关的主要因素。
