Nnaji G A, Ikechebelu J I, Okafor C I
Departments of Primary Health Care, Faculty of Medicine, Nnamdi Azikiwe University, PM.B. 5001, Nnewi Campus, Nigeria.
Niger J Med. 2009 Jul-Sep;18(3):272-6.
To compare the prevalence of malaria parasitaemia and the mean parasite density in pregnant women at first antenatal visit with those of the control subjects at Nnamdi Azikiwe University Teaching Hospital, Nnewi.
A case control prospective survey using a structured questionnaire to collect data from pregnant women attending antenatal clinic between 1 April and 30 September 2001 and matched controls at the GOPD during the same period. Peripheral blood smears were examined in 420 pregnant women at their first antenatal visit and 200 control subjects to compare the prevalence of malaria parasitaemia and mean parasite density in pregnant women and controls.
The prevalence of parasitaemia was 79.3 percent (i.e. 333 of 420) for pregnant women and 31.5 percent (or 63 of 200) for the control. For both pregnant women and controls, an overall prevalence of 63.1 percent was observed. The study found the mean parasite density for the pregnant women to be 1978 +/- 1531 (Mean +/- SD), while that of the controls was 766 +/- 1923.
This study demonstrates the higher prevalence of malaria parasitaemia and mean parasite density in pregnant women when compared with the matched controls.
比较在恩泽维的纳姆迪·阿齐克韦大学教学医院首次产前检查时孕妇的疟疾寄生虫血症患病率和平均寄生虫密度与对照人群的情况。
采用病例对照前瞻性调查，使用结构化问卷收集2001年4月1日至9月30日期间到产前诊所就诊的孕妇以及同期在普通门诊部的匹配对照的数据。对420名首次产前检查的孕妇和200名对照对象进行外周血涂片检查，以比较孕妇和对照人群中疟疾寄生虫血症的患病率和平均寄生虫密度。
孕妇的寄生虫血症患病率为79.3%（即420人中的333人），对照人群为31.5%（200人中的63人）。孕妇和对照人群的总体患病率为63.1%。研究发现孕妇的平均寄生虫密度为1978±1531（均值±标准差），而对照人群为766±1923。
本研究表明，与匹配的对照相比，孕妇的疟疾寄生虫血症患病率和平均寄生虫密度更高。
