Numata Y, Matsuura Y, Onishi S, Yamamoto Y, Ohno F, Tagoh H, Yoshizaki K, Fujimoto S, Yamamoto H
1st Department of Internal Medicine, Kochi Medical School, Japan.
Am J Hematol. 1991 Apr;36(4):282-4. doi: 10.1002/ajh.2830360412.
We examined interleukin-6 production in the hyperplastic lymph node of a 77-year-old male rheumatoid arthritis patient with lymphadenopathy. The interleukin-6 production of the lymph node was observed by both immunohistological staining and in vitro culture. The results suggest that interleukin-6 plays a significant pathogenic role in the etiology of the lymphadenopathy seen in many rheumatoid arthritis patients.
我们检测了一名患有淋巴结病的77岁男性类风湿关节炎患者增生性淋巴结中的白细胞介素-6生成情况。通过免疫组织化学染色和体外培养观察了淋巴结中的白细胞介素-6生成。结果表明，白细胞介素-6在许多类风湿关节炎患者出现的淋巴结病病因中起重要致病作用。
