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流行病学研究中的因果关系。

Causality in epidemiological research.

作者信息

Zieliński Andrzej

机构信息

Zakład Epidemiologii Narodowego Instytutu Zdrowia Publicznego-Państwowego Zakładu Higieny.

出版信息

Przegl Epidemiol. 2009;63(4):557-64.

Abstract

The article presents short historical review of the concepts of causality. Then it deals with contemporary concepts of causal dependence with special reference to epidemiological studies. In particular Lewis counterfactuals theory and contemporary probabilistic theories were analyzed including applications of DAG's (directed acyclic graphs), which in the last decade are frequently applied for presentation of complicated study designs in epidemiology. Authors high appreciation explanatory role of graphic presentation of relationships between variables and the role of conditional probability of events respecting Markov conditions and Bayesian premises, does not change his opinion, that statistical methods are insufficient for final assessment of causal dependence and some subjective element of learned judgment of the scientist has to be always present. In Authors opinion causal approach to associations between are crucial as a base for therapeutic approach and for public health interventions. This is why he is against consequent indeterministic approach.

摘要

本文对因果关系的概念进行了简短的历史回顾。接着探讨了当代因果依赖的概念,特别提及了流行病学研究。具体分析了刘易斯反事实理论和当代概率理论,包括有向无环图(DAG)的应用,在过去十年中,有向无环图经常被用于呈现流行病学中复杂的研究设计。作者高度赞赏变量间关系的图形表示的解释作用以及符合马尔可夫条件和贝叶斯前提的事件条件概率的作用,但这并没有改变他的观点,即统计方法不足以对因果依赖进行最终评估,科学家的学识判断中始终存在一些主观因素。在作者看来,对关联的因果性探讨作为治疗方法和公共卫生干预的基础至关重要。这就是为什么他反对随之而来的非决定论方法。

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