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澳大利亚热带地区的肺炎风险分层:SMART-COP 评分适用吗?

Pneumonia risk stratification in tropical Australia: does the SMART-COP score apply?

机构信息

Menzies School of Health Research and Charles Darwin University, Darwin, NT.

出版信息

Med J Aust. 2010 Feb 1;192(3):133-6. doi: 10.5694/j.1326-5377.2010.tb03450.x.

Abstract

OBJECTIVE

To examine the performance in tropical northern Australia of SMART-COP, a simple scoring system developed in temperate Australia to predict the need for intensive respiratory or vasopressor support (IRVS) in pneumonia patients.

DESIGN, SETTING AND PATIENTS: A prospective observational study of patients admitted to Royal Darwin Hospital in the Northern Territory with sepsis between August 2007 and May 2008. Chest x-rays were reviewed to confirm pneumonia, and each patient's SMART-COP score was assessed against the need for IRVS.

RESULTS

Of 206 patients presenting with radiologically confirmed pneumonia, 184 were eligible for inclusion. The mean age of patients was 50.1 years, 65% were Indigenous and 56% were men. Overall, 38 patients (21%) required IRVS, and 18 patients (10%) died by Day 30. A SMART-COP score of >or= 3 had a sensitivity of only 71% for predicting the need for IRVS and 67% for 30-day mortality. As the variables most strongly associated with IRVS were serum albumin level < 35 g/L (odds ratio, 6.8) and Indigenous status (odds ratio, 2.3), we tested a modified scoring system (SMART-COP) that used a higher weighting for albumin and included Indigenous status. A SMART-COP score of >or= 3 had a sensitivity of 97% for IRVS and 100% for 30-day mortality.

CONCLUSIONS

The SMART-COP score underestimates the severity of pneumonia in tropical northern Australia, but can be improved by using locally relevant additions.

摘要

目的

检验 SMART-COP 在澳大利亚热带北部的表现,这是一种在澳大利亚温带开发的简单评分系统,用于预测肺炎患者是否需要强化呼吸或血管加压支持(IRVS)。

设计、地点和患者:2007 年 8 月至 2008 年 5 月,对北领地皇家达尔文医院因败血症入院的患者进行了一项前瞻性观察性研究。通过胸部 X 光片确认肺炎,并根据需要对每位患者的 SMART-COP 评分进行评估。

结果

在 206 名有放射学确诊肺炎的患者中,有 184 名符合纳入标准。患者的平均年龄为 50.1 岁,65%为土著人,56%为男性。总体而言,38 名患者(21%)需要 IRVS,18 名患者(10%)在第 30 天死亡。SMART-COP 评分>或=3 对预测 IRVS 的敏感性仅为 71%,对 30 天死亡率的敏感性为 67%。由于与 IRVS 最密切相关的变量是血清白蛋白水平<35 g/L(比值比,6.8)和土著身份(比值比,2.3),我们测试了一种改良的评分系统(SMART-COP),该系统对白蛋白的权重更高,并包含土著身份。SMART-COP 评分>或=3 对 IRVS 的敏感性为 97%,对 30 天死亡率的敏感性为 100%。

结论

SMART-COP 评分低估了澳大利亚热带北部肺炎的严重程度,但通过使用当地相关的补充方法可以提高其准确性。

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