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颈动脉动脉瘤的手术修复:一项为期10年的单中心经验。

Surgical repair of carotid artery aneurysms: a 10-year, single-center experience.

作者信息

Srivastava Sunita D, Eagleton Matthew J, O'Hara Patrick, Kashyap Vikram S, Sarac Timur, Clair Daniel

机构信息

Department of Vascular Surgery, S40, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA.

出版信息

Ann Vasc Surg. 2010 Jan;24(1):100-5. doi: 10.1016/j.avsg.2009.09.006.

Abstract

BACKGROUND

The aim of this study was to evaluate the surgical management of carotid artery aneurysms (CAAs) presenting to a tertiary care center over a 10-year period of time.

METHODS

The medical records of patients undergoing repair of CAA between 1998 and 2008 were reviewed. Demographics, clinical presentation, and operative interventions were recorded. Postoperative outcomes were assessed, and patency and survival rates were calculated using life-table analysis.

RESULTS

Two patients (11%) had a history of neck dissection, one (5%) neck irradiation, and three (16%) a combination of neck dissection and irradiation for cancer. Five (26%) had previous carotid endarterectomy, while three (16%) had prior carotid artery stenting for occlusive disease. Eight (42%) patients presented with neurologic symptoms, all transient in nature. Aneurysms were isolated to the internal carotid artery in eight (42%) cases, the common carotid artery in one (5%) case, and both regions in the remaining 53%. The etiologies of the aneurysms were divided among atherosclerotic aneurysms (36.8%), mycotic pseudoaneurysms (36.8%), and patch aneurysms (26.3%).Twelve (63%) underwent resection and interposition grafting, six underwent aneurysm resection and patch repair, and one (5%) had end-to-end reconstruction. Postoperative complications included one transient ischemic attach (5%), two strokes (10%), and one cranial nerve deficit (5%). Primary patency at 30 months was 90% (standard error [SE] = 0.10), and survival at 48 months was 92% (SE = 0.10). Assisted primary patency was maintained at 90% at 30 months (SE = 0.10).

CONCLUSION

CAA surgery, while rare, can be performed safely and with durable patency. Future studies will be necessary to assess the efficacy of endovascular therapy for this disease.

摘要

背景

本研究的目的是评估一家三级医疗中心在10年期间对颈动脉动脉瘤(CAA)的手术治疗情况。

方法

回顾了1998年至2008年间接受CAA修复手术的患者的病历。记录了人口统计学资料、临床表现和手术干预措施。评估术后结果,并使用寿命表分析计算通畅率和生存率。

结果

两名患者(11%)有颈部清扫史,一名(5%)有颈部放疗史,三名(16%)因癌症接受过颈部清扫和放疗联合治疗。五名(26%)曾接受过颈动脉内膜切除术,而三名(16%)曾因闭塞性疾病接受过颈动脉支架置入术。八名(42%)患者出现神经症状,均为短暂性。动脉瘤孤立于颈内动脉的有八例(42%),孤立于颈总动脉的有一例(5%),其余53%累及两个部位。动脉瘤的病因分为动脉粥样硬化性动脉瘤(36.8%)、霉菌性假性动脉瘤(36.8%)和补片动脉瘤(26.3%)。12例(63%)接受了切除和间置移植,6例接受了动脉瘤切除和补片修复,1例(5%)进行了端端重建。术后并发症包括1例短暂性脑缺血发作(5%)、2例中风(10%)和1例脑神经缺损(5%)。30个月时的原发性通畅率为90%(标准误[SE]=0.10),48个月时的生存率为92%(SE=0.10)。30个月时辅助原发性通畅率维持在90%(SE=0.10)。

结论

CAA手术虽然少见,但可以安全进行且通畅持久。未来有必要开展研究评估血管内治疗该病的疗效。

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