Department of Radiology, University of Nebraska Medical Center, Omaha, NE, USA.
Clin Imaging. 2010 Jan-Feb;34(1):1-6. doi: 10.1016/j.clinimag.2009.03.007.
Apparent diffusion coefficients (ADCs) of the brain lesions in primary angiitis of the central nervous system (PACNS) patients were analyzed in this study. The mean ADC ratios for acute/subacute phase lesions were significantly lower than that for chronic phase lesions. However, some acute/subacute phase lesions had elevated ADCs and these lesions disappeared overtime, implicating a nonischemic mechanism in PACNS.
本研究分析了原发性中枢神经系统血管炎(PACNS)患者脑病变的表观扩散系数(ADC)。急性/亚急性期病变的平均 ADC 比值明显低于慢性期病变。然而,一些急性/亚急性期病变的 ADC 值升高,这些病变随时间逐渐消失,提示 PACNS 中存在非缺血性机制。