3-T磁共振血管造影在中枢神经系统原发性血管炎中的应用
3-T magnetic resonance angiography in primary angiitis of the central nervous system.
作者信息
Cosottini Mirco, Canovetti Silvia, Pesaresi Ilaria, Desideri Ilaria, Pizzanelli Chiara, Catarsi Eleonora, Puglioli Michele, Tavoni Antonio, Bonuccelli Ubaldo, Bartolozzi Carlo
机构信息
Department of Neuroscience, University of Pisa, Pisa, Italy.
出版信息
J Comput Assist Tomogr. 2013 Jul-Aug;37(4):493-8. doi: 10.1097/RCT.0b013e31829610e5.
OBJECTIVE
Primary angiitis of the central nervous system (PACNS) is a rare disease characterized by an inflammatory process of intracranial vessels. Magnetic resonance angiography (MRA) (3 T) offers increased signal-to-noise ratio and background suppression, leading to better depiction of the intracranial vessels. The aim of our work was to compare the sensitivity of 3-T MRA to that of 1.5-T MRA in the diagnosis of PACNS.
METHODS
Eight patients with PACNS and signs of angiitis at digital subtraction angiography (DSA) underwent MRA at 1.5 and 3 T. Magnetic resonance angiograms obtained with time-of-flight (TOF) technique were evaluated for the presence of stenosis with respect to DSA.
RESULTS
In PACNS patients, DSA identified 827 intracranial stenoses. Sensitivity for vessel stenosis of 3-T TOF MRA was 47% and 14% for 1.5-T TOF.
CONCLUSIONS
Time-of-flight MRA at 3 T improved the sensitivity of MRA in the noninvasive preliminary evaluation of patients with PACNS.
目的
中枢神经系统原发性血管炎（PACNS）是一种罕见疾病，其特征为颅内血管的炎症过程。磁共振血管造影（MRA）（3T）能提高信噪比并抑制背景，从而更好地显示颅内血管。我们研究的目的是比较3T MRA与1.5T MRA在PACNS诊断中的敏感性。
方法
8例经数字减影血管造影（DSA）显示患有PACNS且有血管炎征象的患者接受了1.5T和3T的MRA检查。采用时间飞跃（TOF）技术获得的磁共振血管造影图像，针对DSA评估狭窄情况。
结果
在PACNS患者中，DSA发现了827处颅内狭窄。3T TOF MRA对血管狭窄的敏感性为47%，1.5T TOF为14%。
结论
3T时间飞跃MRA提高了MRA在PACNS患者无创初步评估中的敏感性。
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