Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.
Clin Imaging. 2010 Jan-Feb;34(1):20-8. doi: 10.1016/j.clinimag.2009.03.012.
Of 31 patients with lung cancer, 19 underwent PET-CT and 12 had CT followed by PET. Thoracic lymph nodes were sampled by mediastinoscopy or thoracotomy. Sensitivities, specificities, positive (PPV), and negative predictive values (NPV) were calculated based on histopathology. Ninety nodes (41 malignant) were identified. Sensitivity, specificity, PPV, and NPV were 94%, 73%, 66%, and 96% for PET-CT, respectively. In 12 patients who underwent PET and CT separately, these values were 90%, 31%, 64%, and 71% for PET and 81%, 50%, 69%, and 66% for CT, respectively.
在 31 名肺癌患者中，19 名接受了 PET-CT 检查，12 名接受了 CT 检查后再进行 PET 检查。经纵隔镜或开胸术对胸内淋巴结进行了取样。根据组织病理学计算了敏感性、特异性、阳性预测值（PPV）和阴性预测值（NPV）。共确定了 90 个淋巴结（41 个恶性）。PET-CT 的敏感性、特异性、PPV 和 NPV 分别为 94%、73%、66%和 96%。在单独接受 PET 和 CT 检查的 12 名患者中，这些值分别为 PET 的 90%、31%、64%和 71%，以及 CT 的 81%、50%、69%和 66%。
