Radiopharmaceuticals Laboratory, Board of Radiation and Isotope Technology (BRIT), Variable Energy Cyclotron Centre (VECC), 1/AF, Bidhan Nagar, Kolkata, India.
Nucl Med Biol. 2010 Jan;37(1):17-20. doi: 10.1016/j.nucmedbio.2009.08.009. Epub 2009 Oct 3.
A simple and inexpensive method has been developed for the separation of (99m)Tc from (99)Mo produced from the neutron activation of (98)Mo by (98)Mo(n,gamma)(99)Mo nuclear reaction. The recovery of (99m)Tc was performed by solid-liquid extraction based on alumina column chromatography. The overall radiochemical yield for the complete separation of (99m)Tc was 85-97% (n=5). The separated Na[(99m)Tc]TcO(4) was of high radionuclidic, radiochemical and chemical purities. The method can be adopted for routine processing and use of (99m)Tc in radiopharmacy operations.
一种简单、廉价的方法已经被开发出来，用于从（98）Mo 经中子活化产生的（99）Mo 中分离（99m）Tc，该方法涉及到（98）Mo(n,gamma)(99)Mo 核反应。（99m）Tc 的回收是通过基于氧化铝柱层析的固液萃取来完成的。完全分离（99m）Tc 的总放射化学收率为 85-97%（n=5）。分离得到的 Na[(99m)Tc]TcO(4) 具有高放射性核纯度、放射化学纯度和化学纯度。该方法可用于放射性药物操作中（99m）Tc 的常规处理和使用。
