Dash Ashutosh, Chakravarty Rubel, Ram Ramu, Pillai K T, Yadav Yugandhara Y, Wagh D N, Verma Rakesh, Biswas Sujoy, Venkatesh Meera
Radiopharmaceuticals Division, Bhabha Atomic Research Centre, Trombay, Mumbai 400085, India.
Appl Radiat Isot. 2012 Jan;70(1):51-8. doi: 10.1016/j.apradiso.2011.07.012. Epub 2011 Jul 29.
A chromatographic (99)Mo/(99m)Tc generator for industrial applications has been developed using alumina microspheres synthesized through sol-gel process to obtain (99m)Tc in both aqueous and non-aqueous media. The sorbent was mesoporous, mechanically strong and possessed high surface area. (99m)Tc could be eluted from generator system using either acetone or 0.9% NaCl solution with appreciably high yields and high radiochemical as well as radionuclidic purity. The facile, versatile generator provides an efficient way to access (99m)Tc at industrial sites for radiotracer applications.
一种用于工业应用的色谱（99）Mo/（99m）Tc发生器已被开发出来，它使用通过溶胶-凝胶法合成的氧化铝微球，以便在水性和非水性介质中获得（99m）Tc。该吸附剂是介孔的，机械强度高且具有高表面积。（99m）Tc可以使用丙酮或0.9%氯化钠溶液从发生器系统中洗脱出来，洗脱产率相当高，放射化学纯度和放射性核素纯度也很高。这种简便、通用的发生器为在工业场所获取用于放射性示踪剂应用的（99m）Tc提供了一种有效的方法。
