脑常染色体显性动脉病伴皮质下梗死和白质脑病（CADASIL）患者出现急性头痛，随后出现局灶性神经认知功能障碍。
Acute headache followed by focal neuropsychological impairment in cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL).
机构信息
Department of Neurology B, Cerebrovascular Unit, Université Lyon 1, Lyon, France.
出版信息
J Stroke Cerebrovasc Dis. 2010 Jan;19(1):75-6. doi: 10.1016/j.jstrokecerebrovasdis.2009.03.001.
Abstract
Occasionally, patients with Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CADASIL) present atypical features such as confusion, coma, or nonconvulsive status epilepticus. Acute focal neuropsychological syndrome revealing the disease has been poorly documented. We report the atypical presentation of two patients in whom CADASIL was revealed by an episode of headache followed by focal neuropsychological impairment.
摘要
偶尔，伴有皮质下梗死和白质脑病的脑常染色体显性遗传性动脉病（CADASIL）患者表现出非典型特征，如意识混乱、昏迷或非惊厥性癫痫持续状态。急性局灶性神经心理综合征揭示该疾病的病例记录很少。我们报告了两例以头痛发作后出现局灶性神经心理障碍为表现的非典型病例，提示 CADASIL 的诊断。
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