Department of Pathology, University of Texas MD Anderson Cancer Center, Houston, USA.
Ann Diagn Pathol. 2010 Feb;14(1):60-7. doi: 10.1016/j.anndiagpath.2009.07.002. Epub 2009 Dec 11.
Sclerosing hemangioma of the lung is a rare neoplasm with polymorphic histologic features. Despite various patterns, there are 2 unifying cellular components: "surface cells" and "round cells." Although histogenesis has been debated for decades, most ultrastructural, immunocytochemical, and molecular studies strongly indicate a neoplastic epithelial derivation for both cellular components. Herein, we present a review of sclerosing hemangioma and summarize the essential data regarding histologic, cytologic, and ancillary findings of this distinctive pulmonary neoplasm.
肺硬化性血管瘤是一种罕见的具有多形性组织学特征的肿瘤。尽管存在各种形态,但有 2 种统一的细胞成分:“表面细胞”和“圆形细胞”。尽管数十年来其组织发生一直存在争议,但大多数超微结构、免疫细胞化学和分子研究强烈表明这两种细胞成分均来源于肿瘤性上皮。本文回顾了硬化性血管瘤,并总结了这种独特的肺肿瘤在组织学、细胞学和辅助检查方面的重要数据。