Cariou Matthieu P L, Halfacree Zoe J, Lee Karla C L, Baines Stephen J
Queen Mother Hospital for Animals, Royal Veterinary College, North Mymms, Hatfield, Hertfordshire AL9 7TA, UK.
J Feline Med Surg. 2010 Jan;12(1):36-41. doi: 10.1016/j.jfms.2009.12.005.
In the veterinary literature, feline gastroduodenal ulcer disease has been described only in individual case reports or retrospective studies reporting small numbers of cats. Although its canine counterpart is commonly encountered, less is known about factors predisposing cats to gastroduodenal ulceration and potentially perforation. Similarly the outcome following treatment is not well reported in this species.
In dogs, hepatic disease and administration of non-steroidal anti-inflammatory drugs (NSAIDs) have been reported as the two most common causes of gastroduodenal ulceration. In cats, only one clinical report so far has implicated an NSAID as a risk factor for spontaneous gastroduodenal perforation.
This report describes the historical and physical findings, as well as the treatment and outcome, in three cats with spontaneous gastric perforation that were receiving anti-inflammatory medication immediately prior to presentation. It highlights the importance of thorough patient evaluation in any cat presenting with non-specific clinical signs and a history of anti-inflammatory drug administration.
在兽医文献中，猫胃十二指肠溃疡病仅在个别病例报告或报告猫数量较少的回顾性研究中有所描述。尽管犬类的同类疾病很常见，但对于猫发生胃十二指肠溃疡及潜在穿孔的易感因素了解较少。同样，该物种治疗后的结果也鲜有报道。
在犬类中，肝脏疾病和非甾体抗炎药（NSAIDs）的使用被报道为胃十二指肠溃疡的两个最常见原因。在猫中，迄今为止仅有一份临床报告表明NSAIDs是自发性胃十二指肠穿孔的一个风险因素。
本报告描述了三只自发性胃穿孔猫的病史、体格检查结果以及治疗和预后情况，这些猫在就诊前均正在接受抗炎药物治疗。它强调了对任何出现非特异性临床症状且有抗炎药物使用史的猫进行全面评估的重要性。
