Department of Urology, Vakif Gureba Training and Research Hospital, Istanbul, Turkey.
Kaohsiung J Med Sci. 2010 Feb;26(2):96-8. doi: 10.1016/s1607-551x(10)70014-0.
We report a 75-year-old female with a primary urethral malignant melanoma. Amass protruding from inside the urethra was detected on physical examination. Abdominopelvic magnetic resonance imaging revealed a mass extending from the urethra with dimensions of 4x2 cm, and periurethral heterogenous fatty planes consistent with infiltration. The histopathologic examination was consistent with HMB45(+) malignant melanoma. We performed cystourethrectomy and bilateral inguinal and pelvic lymphadenectomy in one session. The pathology report revealed primary malignant melanoma of the urethra invading the inferior bladder wall. The patient received no adjuvant therapy because of cardiopulmonary morbidities and the presence of multiple pulmonary metastases. The patient eventually died 13 months after surgery.
我们报告一例 75 岁女性原发性尿道恶性黑色素瘤。体格检查发现尿道内有一肿块突出。腹盆磁共振成像显示尿道内有一肿块，大小为 4x2cm，伴有尿道周围异质性脂肪平面浸润。组织病理学检查符合 HMB45(+)恶性黑色素瘤。我们在一次手术中进行了膀胱尿道切除术和双侧腹股沟及盆腔淋巴结清扫术。病理报告显示原发性尿道恶性黑色素瘤侵犯下膀胱壁。由于心肺疾病和多发性肺转移，患者未接受辅助治疗。术后 13 个月，患者最终死亡。
