Yoshizawa Tsuyoshi, Kawata Nozomu, Sato Katsuhiko, Hirakata Hitoshi, Igarashi Takumi, Ichinose Taketo, Yamaguchi Kenya, Takahashi Satoru
Department of Urology, Nihon University School of Medicine, Tokyo, Japan.
Urology. 2007 Dec;70(6):1222.e13-6. doi: 10.1016/j.urology.2007.09.008.
A case of primary urethral malignant melanoma of a 69-year-old Japanese woman is presented. A hemorrhagic tumor measuring 1 cm in diameter was diagnosed by the stamp method. Clinically, the primary lesion was a T4 tumor infiltrating to the bladder neck, vagina, and vulva. Computed tomography did not detect any inguinal lymph node swelling or metastases to other sites. We selected radical extirpation, including cystectomy, ureterostomy, and bilateral inguinal and pelvic lymph node dissection. Although she subsequently underwent immunochemotherapy, consisting of dacarbazine, nimustine, vincristine, and beta-interferon, she died of the cancer 14 months postoperatively.
本文报告一例69岁日本女性原发性尿道恶性黑色素瘤病例。通过印片法诊断出一个直径1厘米的出血性肿瘤。临床上，原发性病变为T4期肿瘤，浸润至膀胱颈、阴道和外阴。计算机断层扫描未检测到腹股沟淋巴结肿大或其他部位转移。我们选择了根治性切除术，包括膀胱切除术、输尿管造口术以及双侧腹股沟和盆腔淋巴结清扫术。尽管她随后接受了由达卡巴嗪、尼莫司汀、长春新碱和β干扰素组成的免疫化疗，但术后14个月死于癌症。
