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三尖瓣心内膜炎的三尖瓣修复:三尖瓣“再利用”

Tricuspid valve repair for tricuspid valve endocarditis: tricuspid valve "recycling".

作者信息

Allen M D, Slachman F, Eddy A C, Cohen D, Otto C M, Pearlman A S

机构信息

Division of Cardiothoracic Surgery, University of Washington, Seattle.

出版信息

Ann Thorac Surg. 1991 Apr;51(4):593-8. doi: 10.1016/0003-4975(91)90317-j.

Abstract

Tricuspid valve endocarditis traditionally has been treated with either valve excision or valve replacement. To avoid implantation of foreign material in an infected field, we have applied the principles of mitral valve repair to 4 patients with tricuspid valve endocarditis. On preoperative echocardiography, all patients had 3 to 4+ tricuspid regurgitation, evidence of progressive right ventricular enlargement, and mobile vegetations. In each case, up to three quarters of the anterior leaflet was excised en bloc with infected chordae and papillary muscle heads. Surgical procedures included standard quadrangular resection, conversion to a bicuspid valve, and pericardial patch replacement of the anterior leaflet with mobilization of basal chordae to replace resected marginal chordae. On postoperative echocardiography, tricuspid regurgitation and right ventricular dimensions were reduced in 2 of 4 patients in spite of loss of leaflet tissue. All excised valve tissue demonstrated bacteria on Gram stain or culture. Nonetheless, all repaired valves were successfully sterilized without recurrent infections. Tricuspid valve repair can allow eradication of infection with potential for improving valve competency in complicated tricuspid valve endocarditis.

摘要

传统上,三尖瓣心内膜炎的治疗方法是瓣膜切除或瓣膜置换。为避免在感染区域植入异物,我们将二尖瓣修复的原则应用于4例三尖瓣心内膜炎患者。术前超声心动图检查显示,所有患者均有3至4级以上的三尖瓣反流、右心室进行性扩大的证据以及活动的赘生物。在每例手术中,多达四分之三的前叶连同感染的腱索和乳头肌头部被整块切除。手术操作包括标准的四边形切除术、转换为双尖瓣以及用心包补片置换前叶,并将基部腱索移位以替代切除的边缘腱索。术后超声心动图检查显示,尽管有瓣叶组织缺失,但4例患者中有2例的三尖瓣反流和右心室大小有所减小。所有切除的瓣膜组织在革兰氏染色或培养中均发现有细菌。尽管如此,所有修复的瓣膜均成功灭菌,无复发性感染。三尖瓣修复可以根除感染,并有可能改善复杂三尖瓣心内膜炎患者的瓣膜功能。

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