活动型成年脊柱疾病患者广泛融合以下髂骨翼固定的长期结果
Long-term results of iliac wing fixation below extensive fusions in ambulatory adult patients with spinal disorders.
作者信息
Kasten Michael D, Rao Lacey A, Priest Brenda
机构信息
Department of Orthopaedic Surgery, Healthcare Midwest Spine Center, Kalamazoo, MI, USA.
出版信息
J Spinal Disord Tech. 2010 Oct;23(7):e37-42. doi: 10.1097/BSD.0b013e3181cc8e7f.
STUDY DESIGN
Case series, level of evidence therapeutic IV.
OBJECTIVE
Examine the results of bilateral iliac wing fixation in long fusions to the pelvis in ambulatory adult patients.
SUMMARY OF BACKGROUND DATA
Adult spinal deformity surgery is an endeavor often fraught with complications. One particularly debilitating problem with long fusions of the spine in adults with spinal diseases such as degenerative scoliosis and spondylolysis is failure of the lumbosacral (spinal-pelvic) junction owing to nonunion, implant failure, or sacral fracture. This can result in continued pain, continued curve progression and deformity, progressive sagittal imbalance, and the need for reoperation. Some deformity surgeons have speculated fusion rates at the caudal end of long constructs to the sacrum could be improved by the addition of spinopelvic fixation. Iliac wing screws have been successfully used in nonambulatory patients for the treatment of neuromuscular scoliosis, but concerns exist over use in ambulatory patients. Prominence, local irritation of the screws, screw breakage, infection, and sacroiliac joint pathology are all concerns. The purpose of this study was to examine the results of long fusions to the sacrum using bilateral iliac wing screw fixation in ambulatory adults with spinal deformities.
METHODS
This case series consisted of 78 patients followed for at least 2 years (average 3.7 y, range: 2 to 8 y). All patients were ambulatory adults who received bilateral iliac wing fixation below long fusion constructs (average 9 levels fused). All but 3 patients were above 50 years old and the average age in the study was 67.6 years. There were 66 females and 12 males in the study. The operative indications for posterior spinal fusion were fixed sagittal imbalance spondylolysis (23 patients), idiopathic scoliosis (22 patients), degenerative scoliosis (15 patients), pseudarthrosis below long fusions (13 patients), and traumatic kyphosis (5 patients). Patients were analyzed clinically and radiographically and all complications were noted. Correction of coronal deformity and correction of fixed sagittal imbalance were measured by comparing preoperative and postoperative radiographic measurements. All patients completed the Zuckerman written questionnaire to assess patient's subjective clinical result.
RESULTS
Twelve of 78 patients (15.3%) developed pseudarthrosis with broken implants; however only 5 of 78 (6.4%) nonunions occurred at the lumbosacral junction. Six of 78 patients (7.7%) required removal of the iliac screws for pain or painful prominence. Forty-two patients had one or more complications with an overall complication rate of 54%. Despite the overall complication and revision rate, 78% of patients reported good or excellent results with the Zuckerman questionnaire. Excellent correction of sagittal balance and coronal deformity was achieved. Average sagittal balance preoperatively was+10 and improved to an average of+2.5 postoperatively. Average major curve coronal plane deformity preoperatively was 61 degree and improved to an average of 29 degree postoperatively. There were no sacral fractures, sacral screw failures, or significant sacroiliac joint degeneration on follow-up radiographs.
CONCLUSIONS
In this series, nonunions continue to be a problem, with a rate of 15.3%, however only 6.4% of nonunions were at the lumbosacral junction. Complications specific to iliac screw placement were minimal. These difficult surgeries are known to be plagued with problems and our complication rate is consistent with what is present in the current literature. The use of iliac wing fixation seems to dramatically improve lumbosacral fusion rates with an acceptable complication rate; in addition there seems to be a protective effect in preventing sacral fractures, sacral screw failure, and sacroiliac arthritis.
研究设计
病例系列,证据等级为治疗性IV级。
目的
研究在能行走的成年患者中,双侧髂骨翼固定用于脊柱与骨盆长节段融合的效果。
背景资料总结
成人脊柱畸形手术常常充满并发症。对于患有退行性脊柱侧凸和椎弓根峡部裂等脊柱疾病的成年人,脊柱长节段融合时一个特别使人衰弱的问题是腰骶(脊柱-骨盆)连接部因骨不连、植入物失败或骶骨骨折而出现问题。这可能导致持续疼痛持续的侧弯进展和畸形、矢状面失衡加重以及再次手术的需要。一些脊柱畸形外科医生推测,通过增加脊柱骨盆固定,可以提高长节段固定结构尾端与骶骨的融合率。髂骨翼螺钉已成功用于非行走患者治疗神经肌肉型脊柱侧凸,但对于其在行走患者中的应用存在担忧。螺钉突出、局部刺激、螺钉断裂、感染以及骶髂关节病变都是需要关注的问题。本研究的目的是研究在能行走的脊柱畸形成年患者中,使用双侧髂骨翼螺钉固定进行脊柱与骶骨长节段融合的效果。
方法
本病例系列包括78例随访至少2年(平均3.7年,范围:2至8年)的患者。所有患者均为能行走的成年人,在长节段融合结构下方接受双侧髂骨翼固定(平均融合9个节段)。除3例患者外,所有患者年龄均超过50岁,研究中的平均年龄为67.6岁。研究中有66名女性和12名男性。后路脊柱融合的手术指征为固定性矢状面失衡、椎弓根峡部裂(23例患者)、特发性脊柱侧凸(22例患者)、退行性脊柱侧凸(15例患者)、长节段融合下方的假关节(13例患者)以及创伤性后凸(5例患者)。对患者进行临床和影像学分析,并记录所有并发症。通过比较术前和术后的影像学测量结果,评估冠状面畸形的矫正情况和固定性矢状面失衡的矫正情况。所有患者均完成了Zuckerman书面问卷,以评估患者的主观临床结果。
结果
78例患者中有12例(15.3%)出现假关节伴植入物断裂;然而,78例中只有5例(6.4%)在腰骶连接部发生骨不连。78例患者中有6例(7.7%)因疼痛或螺钉突出疼痛而需要取出髂骨螺钉。42例患者出现一种或多种并发症,总体并发症发生率为54%。尽管总体并发症和翻修率较高,但78%的患者在Zuckerman问卷中报告结果良好或优秀。矢状面平衡和冠状面畸形得到了出色的矫正。术前矢状面平均平衡为+10,术后平均改善至+2.5。术前主要侧弯冠状面平均畸形为61度,术后平均改善至29度。随访X线片显示无骶骨骨折、骶骨螺钉失败或明显的骶髂关节退变。
结论
在本系列中,骨不连仍然是一个问题,发生率为15.3%,然而只有6.4%的骨不连发生在腰骶连接部。髂骨螺钉置入特有的并发症极少。这些复杂手术已知存在诸多问题,我们报告的并发症发生率与当前文献报道一致。使用髂骨翼固定似乎能显著提高腰骶融合率,且并发症发生率可接受;此外,在预防骶骨骨折、骶骨螺钉失败和骶髂关节炎方面似乎有保护作用。