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成人脊柱畸形中长节段融合至骶骨的结果与并发症:Luque-Galveston术、髂骨与骶骨联合螺钉固定术及骶骨固定术

Outcome and complications of long fusions to the sacrum in adult spine deformity: luque-galveston, combined iliac and sacral screws, and sacral fixation.

作者信息

Emami Arash, Deviren Vedat, Berven Sigurd, Smith Jason A, Hu Serena S, Bradford David S

机构信息

University of California, San Francisco, USA.

出版信息

Spine (Phila Pa 1976). 2002 Apr 1;27(7):776-86. doi: 10.1097/00007632-200204010-00017.

Abstract

STUDY DESIGN

A retrospective study of adults with long fusion to the sacrum using three different fixations was performed.

OBJECTIVE

To compare the long-term clinical results and complications associated with three methods of lumbosacral fixation for adult spine deformities: Luque-Galveston, combined iliac and sacral screws, and sacral screws.

SUMMARY OF BACKGROUND DATA

The preferred technique for long fusion to the sacrum is controversial, and surgery for adult deformity is fraught with significant technical difficulties and high complication rates. No clinical study compares the long-term outcome of long fusion to the sacrum using these different methods of lumbosacral fixation.

METHODS

This study included 54 consecutive patients who underwent elective combined anterior and posterior surgical reconstruction for adult spine deformity with a minimum follow-up period of 2 years. The patients were divided into three groups on the basis of the surgical method used for the posterior spine instrumentation. Group 1 consisted of 11 patients with smooth L-rod and segmental sublaminar wire instrumentation (Luque-Galveston technique). Group 2 consisted of 36 patients with posterior Isola segmental instrumentation and combined iliac and sacral screws. Group 3 consisted of 12 patients with Isola segmental instrumentation using bicortical sacral screws. Five patients were revised to another fixation group, giving a total of 59 cases. Radiographic, clinical results, and long-term outcome data were obtained using the modified Scoliosis Research Society (SRS) outcome instrument.

RESULTS

There were 26 late complications. Pseudarthrosis developed in 10 patients, requiring revision surgery: 4 (36%) in the Group 1, 5 (14%) in Group 2, and 1 (8.5%) in Group 3. Comparison of the modified SRS outcomes showed no difference among the groups. The average SRS grand total score was 73.4% for Group 1, 70.9% for Group 2, and 62.6% for Group 3. Overall, 76% of the patients were satisfied with their outcome. The presence of perioperative complications or pseudarthrosis significantly correlated with a lower satisfaction score (P = 0.012 and P = 0.048, respectively). Sagittal plane decompensation significantly correlated with a higher pain score (P = 0.035). Patients with prior surgeries scored lower on the self-image questions than patients with no prior surgery (P = 0.007).

CONCLUSIONS

Attention to sagittal balance is critical in these patients. Revision surgery is as safe and effective as primary surgery. According to the current findings, the Luque-Galveston fixation technique has an unacceptably high rate of pseudarthrosis, and this method is not recommended for adult deformities. Currently, the authors are using bicortical and triangulated sacral screws with an anterior interbody support in patients with good bone stock, but only when the spine balance is restored. Otherwise, they recommend using iliac fixation, although there is a higher rate of painful hardware, requiring removal.

摘要

研究设计

对采用三种不同固定方式与骶骨进行长节段融合的成人患者进行回顾性研究。

目的

比较用于成人脊柱畸形的三种腰骶部固定方法(即Luque - Galveston法、髂骨与骶骨螺钉联合固定法以及骶骨螺钉固定法)的长期临床效果及并发症。

背景资料总结

与骶骨进行长节段融合的首选技术存在争议,并且成人畸形手术充满了重大技术难题和高并发症发生率。尚无临床研究比较使用这些不同腰骶部固定方法与骶骨进行长节段融合的长期结果。

方法

本研究纳入54例连续接受成人脊柱畸形择期前后路联合手术重建且随访期至少2年的患者。根据后路脊柱内固定所采用的手术方法将患者分为三组。第1组由11例采用平滑L形棒及节段性椎板下钢丝固定(Luque - Galveston技术)的患者组成。第2组由36例采用后路Isola节段性内固定及髂骨与骶骨螺钉联合固定的患者组成。第3组由12例采用双皮质骶骨螺钉的Isola节段性内固定患者组成。5例患者被改为另一固定组,共计59例。使用改良的脊柱侧弯研究学会(SRS)结局评估工具获取影像学、临床结果及长期结局数据。

结果

出现26例晚期并发症。10例患者发生假关节形成,需要翻修手术:第1组4例(36%),第2组5例(14%),第3组1例(8.5%)。改良SRS结局比较显示各组间无差异。第1组SRS总分平均为73.4%,第2组为70.9%,第3组为62.6%。总体而言,76%的患者对其结局满意。围手术期并发症或假关节的存在与较低的满意度评分显著相关(分别为P = 0.012和P = 0.048)。矢状面失代偿与较高的疼痛评分显著相关(P = 0.035)。有既往手术史的患者在自我形象问题上的得分低于无既往手术史的患者(P = 0.007)。

结论

关注矢状面平衡对这些患者至关重要。翻修手术与初次手术一样安全有效。根据目前的研究结果,Luque - Galveston固定技术假关节形成率高得令人无法接受,不推荐用于成人畸形。目前,作者在骨质良好的患者中使用双皮质及三角形骶骨螺钉并辅以椎间支撑,但仅在脊柱平衡恢复时使用。否则,他们建议采用髂骨固定,尽管硬件相关疼痛发生率较高且需要取出。

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