Department of Anesthesiology, Erasmus University Medical Center, Rotterdam, the Netherlands.
Anesthesiology. 2010 Mar;112(3):557-66. doi: 10.1097/ALN.0b013e3181ce9d67.
Coronary revascularization of the suspected culprit coronary lesion assessed by preoperative stress testing is not associated with improved outcome in vascular surgery patients.
Fifty-four major vascular surgery patients underwent preoperative dobutamine echocardiography and intraoperative transesophageal echocardiography. The locations of left ventricular rest wall motion abnormalities and new wall motion abnormalities (NWMAs) were scored using a seven-wall model. During 30-day follow-up, postoperative cardiac troponin release, myocardial infarction, and cardiac death were noted.
Rest wall motion abnormalities were noted by dobutamine echocardiography in 17 patients (31%), and transesophageal echocardiography was noted in 16 (30%). NWMAs were induced during dobutamine echocardiography in 17 patients (31%), whereas NWMAs were observed by transesophageal echocardiography in 23 (43%), kappa value = 0.65. Although preoperative and intraoperative rest wall motion abnormalities showed an excellent agreement for the location (kappa value = 0.92), the agreement for preoperative and intraoperative NWMAs in different locations was poor (kappa value = 0.26-0.44). The composite cardiac endpoint occurred in 14 patients (26%).
There was a poor correlation between the locations of preoperatively assessed stress-induced NWMAs by dobutamine echocardiography and those observed intraoperatively using transesophageal echocardiography. However, the composite endpoint of outcome was met more frequently in relation with intraoperative NWMAs.
术前应激试验评估的可疑罪犯冠状动脉病变的血运重建与血管外科患者的预后改善无关。
54 例大型血管外科患者接受术前多巴酚丁胺超声心动图和术中经食管超声心动图检查。采用七壁模型对左心室静息壁运动异常和新壁运动异常(NWMAs)的部位进行评分。在 30 天随访期间,记录术后心脏肌钙蛋白释放、心肌梗死和心脏性死亡的情况。
多巴酚丁胺超声心动图发现 17 例(31%)患者存在静息壁运动异常,16 例(30%)经食管超声心动图发现静息壁运动异常。多巴酚丁胺超声心动图诱导 17 例(31%)患者发生 NWMAs,而经食管超声心动图观察到 23 例(43%)患者发生 NWMAs,kappa 值为 0.65。尽管术前和术中静息壁运动异常在位置上具有极好的一致性(kappa 值=0.92),但不同位置的术前和术中 NWMAs 的一致性较差(kappa 值=0.26-0.44)。14 例患者(26%)出现复合心脏终点。
术前多巴酚丁胺超声心动图评估的应激诱导 NWMAs 与术中经食管超声心动图观察到的位置相关性较差。然而,与术中 NWMAs 相关的复合终点出现的频率更高。