Anestesia e Rianimazione SSN, Azienda Ospedaliera-Universitaria Pisana, Pisa, Italy.
Curr Opin Anaesthesiol. 2010 Apr;23(2):128-32. doi: 10.1097/ACO.0b013e328337260a.
This review aims to identify specific criteria for cirrhotic cardiomyopathy, examine the correlation with perioperative adverse outcomes and explore options for hemodynamic monitoring.
Cirrhotic cardiomyopathy is characterized by an increase in cardiac output, blunted systolic contractile response to stress, diastolic dysfunction and electrophysiological abnormalities. Adverse events due to cirrhotic cardiomyopathy are not as well characterized, but evidence suggests that some cardiovascular complications during surgery and in the postoperative period are caused by an impaired response to physiological stress. New developments in hemodynamic monitoring using not only thermodilution technology provide more reliable information about cardiac performance than pressure-derived measures. Transesophogeal echocardiography also offers the physician new information including the ability to visualize heart structures, shape, and function.
To detect cirrhotic cardiomyopathy, physicians must conduct a systematic examination of the patient. Overt manifestations of cirrhotic cardiomyopathy often only become evident after a patient is exposed to physiological or drug-induced stress. Appropriate hemodynamic monitoring is a cornerstone in the perioperative management of cirrhotic patients.
本文旨在确定肝硬化性心肌病的具体标准,探讨其与围手术期不良结局的相关性,并研究血流动力学监测的选择。
肝硬化性心肌病的特征是心输出量增加、对压力的收缩反应减弱、舒张功能障碍和电生理异常。肝硬化性心肌病的不良事件特征尚不明确,但有证据表明,手术期间和术后的一些心血管并发症是由于对生理应激的反应受损引起的。血流动力学监测的新进展不仅使用热稀释技术,还提供了比压力衍生指标更可靠的心脏功能信息。经食管超声心动图还为医生提供了包括可视化心脏结构、形状和功能的新信息。
为了检测肝硬化性心肌病,医生必须对患者进行系统检查。肝硬化性心肌病的明显表现通常仅在患者暴露于生理或药物诱导的应激后才会出现。适当的血流动力学监测是肝硬化患者围手术期管理的基石。