Sakamoto H, Uda H, Tanaka T, Oda T, Morino H, Kikui M
Department of Pathology, Kagawa Medical School, Japan.
Arch Pathol Lab Med. 1991 Apr;115(4):393-6.
A pleomorphic adenoma of the lung recurred after 9 years. The primary tumor consisted mainly of cartilaginous and fibrous elements with a small area of epithelial cell nests, whereas the second one possessed epithelial cell nests with cartilaginous stroma. Immunohistochemical studies showed that both tumors had neoplastic cells with immunoreactive S100, keratin, actin, vimentin, and glial fibrillary acid protein-positive cytoplasm. The primary tumor, which was resected from the periphery of the lung, was not connected with the trachea or the bronchus macroscopically. To our knowledge, the literature contains only six reports of pleomorphic adenoma in the lung.
一例肺多形性腺瘤9年后复发。原发肿瘤主要由软骨和纤维成分组成，伴有小面积上皮细胞巢，而复发肿瘤则为带有软骨基质的上皮细胞巢。免疫组织化学研究显示，两个肿瘤的肿瘤细胞胞质中S100、角蛋白、肌动蛋白、波形蛋白和胶质纤维酸性蛋白免疫反应均呈阳性。从肺外周切除的原发肿瘤在大体上与气管或支气管无连接。据我们所知，文献中仅有6例肺多形性腺瘤的报道。
