Shaping science policy: what's happening to biomedical research in America.

There is, scientists proclaim, a crisis in biomedical research. The crisis lies in the fact that the community's expectations now exceed any reasonable capacity to fund its projects. Between the late 1960s and now, the community has felt threatened many times: by the government leaders' and the public's perceptions of what basic science can produce; by such government initiatives as the "war on cancer," which steered funding to politically chosen areas of research; by changes in funding postgraduate research training; and by successive "crises" over the way NIH research funds are apportioned. None of these crises has resulted in the predicted dire consequences for the community, and the current one will not either. The challenge for the biomedical research community is to set priorities and allocate money accordingly. Despite the nation's economic and social problems, funding for biomedical research remains very high--$8 billion for the NIH, for example--and the community cannot expect that doubling or even tripling the budget would fund all the good ideas produced by a greatly expanded body of researchers. New policies for allocating funds among individual investigators, institutions, and infrastructure need to be put in place.