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颈挥鞭伤相关性疾病:谁会抑郁?谁会持续抑郁?

Whiplash-associated disorders: who gets depressed? Who stays depressed?

机构信息

Department of Public Health Sciences, Alberta Centre for Injury Control and Research, School of Public Health, University of Alberta, 4075 RTF, 8308 114 St, Edmonton, AB, T6G 2E1, Canada.

出版信息

Eur Spine J. 2010 Jun;19(6):945-56. doi: 10.1007/s00586-010-1276-2. Epub 2010 Feb 2.

Abstract

Depression is common in whiplash-associated disorders (WAD). Our objectives were to identify factors associated with depressive symptomatology occurring in the initial stages of WAD, and to identify factors predicting the course of depressive symptoms. A population-based cohort of adults sustaining traffic-related WAD was followed at 6 weeks, 3, 6, 9, and 12 months. Baseline measures (assessed a median of 11 days post-crash) included demographic and collision-related factors, prior health, and initial post-crash pain and symptoms. Depressive symptomatology was assessed at baseline and at each follow-up using the Centre for Epidemiological Studies Depression Scale (CES-D). We included only those who participated at all follow-ups (n = 3,452; 59% of eligible participants). Using logistic regression, we identified factors associated with initial (post-crash) depression. Using multinomial regression, we identified baseline factors predicting course of depression. Courses of depression were no depression; initial depression that resolves, recurs or persists, and later onset depression. Factors associated with initial depression included greater neck and low back pain severity, greater percentage of body in pain, numbness/tingling in arms/hand, dizziness, vision problems, post-crash anxiety, fracture, prior mental health problems, and poorer general health. Predictors of persistent depression included older age, greater initial neck and low back pain, post-crash dizziness, vision and hearing problems, numbness/tingling in arms/hands, anxiety, prior mental health problems, and poorer general health. Recognition of these underlying risk factors may assist health care providers to predict the course of psychological reactions and to provide effective interventions.

摘要

抑郁在挥鞭样损伤相关疾病(WAD)中很常见。我们的目的是确定与 WAD 初始阶段出现的抑郁症状相关的因素,并确定预测抑郁症状病程的因素。对因交通相关 WAD 受伤的成年人进行了一项基于人群的队列研究,在 6 周、3 个月、6 个月、9 个月和 12 个月时进行随访。基线测量(在碰撞后中位数 11 天评估)包括人口统计学和碰撞相关因素、既往健康状况以及初始碰撞后疼痛和症状。使用流行病学研究中心抑郁量表(CES-D)在基线和每次随访时评估抑郁症状。我们仅纳入了所有随访参与者(n=3452;符合条件参与者的 59%)。使用逻辑回归,我们确定了与初始(碰撞后)抑郁相关的因素。使用多项回归,我们确定了预测抑郁病程的基线因素。抑郁的病程包括无抑郁;初始抑郁缓解、复发或持续存在,以及后期发生抑郁。与初始抑郁相关的因素包括颈部和下背部疼痛更严重、身体疼痛百分比更高、手臂/手部麻木/刺痛、头晕、视力问题、碰撞后焦虑、骨折、既往心理健康问题和整体健康状况较差。持续性抑郁的预测因素包括年龄较大、初始颈部和下背部疼痛更大、碰撞后头晕、视力和听力问题、手臂/手部麻木/刺痛、焦虑、既往心理健康问题和整体健康状况较差。识别这些潜在的风险因素可能有助于医疗保健提供者预测心理反应的病程,并提供有效的干预措施。

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