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后路入路治疗腹侧脊髓脊膜瘤。

Posterior approach to ventrally located spinal meningiomas.

机构信息

Department of Neurosurgery, University Hospital of Ioannina, PO BOX 103, Neohoropoulo, 45500, Ioannina, Greece.

出版信息

Eur Spine J. 2010 Jul;19(7):1195-9. doi: 10.1007/s00586-010-1295-z. Epub 2010 Feb 3.

Abstract

For the resection of anteriorly located meningiomas, various approaches have been used. Posterior approach is less invasive and demanding; however, it has been associated with increased risk of spinal cord injury. We evaluated ten consecutive patients that underwent surgery for spinal meningiomas. All patients were preoperative assessed by neurological examination, computed tomography and magnetic resonance imaging. All tumors were ventrally located and removed via a posterior approach. Transcranial motor-evoked potentials (TcMEPs), somatosensory-evoked potential (SSEP) and free running electromyography (EMG) were monitored intraoperative. Postoperative all patients had regular follow-up examinations. There were four males and six females. The mean age was 68.2 years (range 39-82 years). In nine out of ten cases, the tumor was located in the thoracic spine. A case of a lumbar meningioma was recorded. The most common presenting symptom was motor and sensory deficits and unsteady gait, whereas no patient presented with paraplegia. All meningiomas were operated using a microsurgical technique via a posterior approach. During the operation, free running EMG monitoring prompted a surgical alert in case of irritation, whereas TcMEP and SSEP amplitudes remained unchanged. Histopathology revealed the presence of typical (World Health Organisation grade I) meningiomas. The mean Ki-67/MIB-1 index was 2.75% (range 0.5-7). None of our patients sustained a transient or permanent motor deficit. After a mean follow-up period of 26 months (range 56-16 months), no tumor recurrence and no instability were found. Posterior approach for anteriorly located meningiomas is a safe procedure with the use of intraoperative monitoring, less invasive and well-tolerated especially in older patients. Complete tumor excision can be performed with satisfactory results.

摘要

对于位于前部的脑膜瘤,已经使用了各种方法进行切除。后路方法侵袭性较小且要求较低;然而,它与脊髓损伤的风险增加有关。我们评估了 10 例连续接受脊柱脑膜瘤手术的患者。所有患者均通过神经学检查、计算机断层扫描和磁共振成像进行术前评估。所有肿瘤均位于腹侧,并通过后路切除。术中监测颅外运动诱发电位(TcMEPs)、体感诱发电位(SSEP)和自由运行肌电图(EMG)。所有患者术后均进行定期随访检查。其中 4 例为男性,6 例为女性。平均年龄为 68.2 岁(范围 39-82 岁)。在 10 例病例中,肿瘤位于胸椎。记录了一例腰椎脑膜瘤。最常见的表现症状是运动和感觉障碍以及步态不稳,而没有患者出现截瘫。所有脑膜瘤均通过后路显微外科技术进行手术。在手术过程中,自由运行 EMG 监测在受到刺激时会发出手术警报,而 TcMEP 和 SSEP 幅度保持不变。组织病理学显示存在典型(世界卫生组织分级 I)脑膜瘤。平均 Ki-67/MIB-1 指数为 2.75%(范围 0.5-7)。我们的患者均未出现短暂或永久性运动障碍。平均随访 26 个月(范围 56-16 个月)后,未发现肿瘤复发和不稳定。对于位于前部的脑膜瘤,后路方法是一种安全的手术方法,术中监测可降低侵袭性,特别适合老年患者,并且耐受性良好。可以进行完整的肿瘤切除,获得满意的效果。

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