Department of Gastroenterology, Renmin Hospital of Wuhan University, Jiefang Road 238, Wuhan 430060, Hubei Province, China.
World J Gastroenterol. 2010 Feb 7;16(5):631-5. doi: 10.3748/wjg.v16.i5.631.
To investigate the incidence, location, clinical presentation, diagnosis and effectiveness of endoscopic treatment of gastric Dieulafoy's lesion (DL) in China.
All patients who received emergency upper gastrointestinal (GI) endoscopy due to gastric DL from February 2000 to August 2008 at GI endoscopy center of Renmin Hospital of Wuhan University were included in this study. The clinical presentation, medical history, location and characteristics of DL methods and effectiveness of therapy of patients with DL were retrospectively analysed by chart reviews. Long-term follow-up data were collected at outpatient clinics or telephone interviews.
Fifteen patients were diagnosized with DL, which account for 1.04% of the source of bleeding in acute non-variceal upper GI bleeding. Common comorbidities were found in one patient with hypertension and diabetic mellitus. Hemoclip or combined therapy with hemoclip produced primary hemostasis in 92.8% (13/14) of patients.
DL is uncommon but life-threatening in China. Hemoclip proved to be safe and effective in controlling bleeding from DL.
调查中国胃底恒径动脉（DL）病变内镜治疗的发生率、部位、临床表现、诊断和疗效。
本研究纳入了 2000 年 2 月至 2008 年 8 月期间，在武汉大学人民医院内镜中心因胃 DL 接受紧急上消化道（GI）内镜检查的所有患者。通过病历回顾，分析了患者的临床表现、病史、DL 的位置和特征、以及 DL 患者的治疗方法和疗效。通过门诊或电话访谈收集了长期随访数据。
15 例患者被诊断为 DL，占急性非静脉曲张性上 GI 出血的出血源的 1.04%。1 例患者同时患有高血压和糖尿病。在 92.8%（13/14）的患者中，使用止血夹或联合止血夹治疗可达到初步止血的效果。
在中国，DL 虽然不常见，但具有生命威胁性。止血夹在控制 DL 出血方面被证明是安全有效的。
