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一项比较临床研究,评估一种新型敏感美白牙膏与市售美白牙膏相比的污渍清除效果。

A comparative clinical study evaluating stain removal efficacy of a new sensitivity whitening dentifrice compared to commercially available whitening dentifrices.

作者信息

Hughes Nathan, Maggio Brenda, Sufi Farzana, Mason Stephen, Kleber Carl J

机构信息

GlaxoSmithKline Consumer Healthcare, Weybridge, UK.

出版信息

J Clin Dent. 2009;20(7):218-22.

Abstract

OBJECTIVE

To assess the extrinsic stain removal efficacy of a new sensitivity dentifrice containing sodium tripolyphosphate (STP) to marketed whitening toothpastes after six weeks of product use.

METHODS

This was a single-center, double-blind, stratified, six-week clinical study comparing the reduction in stain area and intensity of Sensodyne Extra Whitening to Crest Maximum Strength Sensitivity Protection Whitening plus Scope and Colgate Tartar Control Plus Whitening Mint dentifrice, as measured by MacPherson's Modification of the Lobene Stain Index (MMLSI) in a forced stain model.

RESULTS

Two-hundred and ninety-five subjects completed the study. Tooth stain MMSLI scores showed significant differences between Sensodyne and Crest dentifrices in favor of Sensodyne for all surface sites (p = 0.014), and individually for facial (p = 0.023), lingual (p = 0.027), and interproximal (p = 0.014) surfaces. No significant statistical differences between Sensodyne and Colgate dentifrices were observed for any of the surfaces.

CONCLUSION

Results from this stain removal clinical study demonstrate significant extrinsic stain removal efficacy for all dentifrices relative to baseline. Significant differences between the two marketed sensitivity whitening dentifrices were demonstrated in favor of the new Sensodyne Sensitivity Whitening dentifrice.

摘要

目的

评估一种含三聚磷酸钠(STP)的新型脱敏牙膏在使用六周后相对于市售美白牙膏去除外源性色斑的效果。

方法

这是一项单中心、双盲、分层、为期六周的临床研究,在强制色斑模型中,通过麦克弗森对洛贝内色斑指数(MMLSI)的改良来比较舒适达Extra Whitening牙膏与佳洁士超强抗敏美白牙膏加Scope漱口水以及高露洁防垢加美白薄荷牙膏在色斑面积减少和色斑强度方面的差异。

结果

295名受试者完成了研究。牙齿色斑MMSLI评分显示,舒适达牙膏和佳洁士牙膏在所有牙面部位存在显著差异,舒适达牙膏更具优势(p = 0.014),在唇面(p = 0.023)、舌面(p = 0.027)和邻面(p = 0.014)单独比较时也是如此。舒适达牙膏和高露洁牙膏在任何牙面均未观察到显著统计学差异。

结论

这项色斑去除临床研究结果表明,所有牙膏相对于基线均具有显著的外源性色斑去除效果。两种市售脱敏美白牙膏之间存在显著差异,新型舒适达脱敏美白牙膏更具优势。

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