Leone Sebastiano, Giglio Sergio, Maio Patrizia, Capasso Piero, dell'Aquila Giuseppina, Magliocca Mario, Nigro Francesco Saverio, Pacifico Piera, Acone Nicola
Infectious Diseases Division, A.O.R.N. San G. Moscati, Avellino, Italy.
New Microbiol. 2009 Oct;32(4):415-7.
Highly active antiretroviral therapy (HAART) has been shown to induce a major and durable viral load reduction accompanied by a stable CD4 increase. This process may evolve with adverse clinical phenomena, known as the immune reconstitution inflammatory syndrome (IRIS). In the HIV population, non-tuberculous mycobacteria are a common cause of IRIS. However, only a few cases of Mycobacterium xenopi associated IRIS have been described. This paper concerns a case of M. xenopi pulmonary infection resulting in self-limited immune reconstitution inflammatory syndrome in an HIV-1 infected patient.
高效抗逆转录病毒疗法（HAART）已被证明可使病毒载量显著且持久降低，并伴有CD4细胞稳定增加。这一过程可能会伴有不良临床现象，即免疫重建炎症综合征（IRIS）。在艾滋病毒感染者中，非结核分枝杆菌是IRIS的常见病因。然而，仅有少数关于偶发分枝杆菌所致IRIS的病例报道。本文涉及一例偶发分枝杆菌肺部感染导致HIV-1感染患者出现自限性免疫重建炎症综合征的病例。
