一名感染HIV的麻风病患者在开始高效抗逆转录病毒治疗（HAART）后出现严重的周围神经病变。

Severe peripheral neuropathy following HAART initiation in an HIV-infected patient with leprosy.

作者信息

Pavie Juliette, De Castro Nathalie, Molina Jean-Michel, Flageul Beatrice

机构信息

Department of Infectious Diseases, Saint Louis Hospital and University of Paris Diderot, Paris, France.

出版信息

J Int Assoc Physicians AIDS Care (Chic). 2010 Jul-Aug;9(4):232-5. doi: 10.1177/1545109710373829.

DOI:10.1177/1545109710373829

PMID:20798403

Abstract

We report a case of peripheral neuropathy following highly active antiretroviral therapy (HAART) initiation in a patient coinfected with HIV and Mycobacterium leprae and review the literature on leprosy-associated immune reconstitution inflammatory syndrome (IRIS). Physicians in charge of HIV-infected patients originating from countries endemic for leprosy should be aware of this risk of leprosy-associated IRIS when starting HAART.

摘要

我们报告了一例同时感染人类免疫缺陷病毒（HIV）和麻风分枝杆菌的患者在开始高效抗逆转录病毒治疗（HAART）后发生周围神经病变的病例，并综述了关于麻风相关免疫重建炎症综合征（IRIS）的文献。负责治疗来自麻风流行国家的HIV感染患者的医生在开始HAART时应意识到这种麻风相关IRIS的风险。