Cole Eye Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA.
Ocul Immunol Inflamm. 2010 Jan;18(1):16-8. doi: 10.3109/09273940903312005.
A 50-year-old woman with a history of anti-Jo1-positive inflammatory myositis and interstitial lung disease presented with decreased vision in her right eye. Examination revealed white-centered hemorrhages scattered across the posterior pole in addition to several areas of vascular sheathing. Treatment was initiated with intravenous pulse solumedrol, with improvement in vision and resolution of the patient's white-centered hemorrhages. A thorough workup for other causes of vasculitis was unrevealing. Anti-synthetase syndrome is a serologically defined disorder clinically characterized by inflammatory myositis, interstitial lung disease, and other systemic findings. To our knowledge, retinal vasculitis has not been previously reported in patients with anti-synthetase syndrome.
一位 50 岁的女性，有抗 Jo1 阳性炎性肌病和间质性肺病的病史，出现右眼视力下降。检查发现后极部散布着白色中心的出血，并有几个血管鞘区域。给予静脉注射脉冲甲泼尼龙治疗，视力改善，患者的白色中心出血消退。对其他血管炎原因的全面检查没有发现异常。抗合成酶综合征是一种血清学定义的疾病，临床上以炎性肌病、间质性肺病和其他全身表现为特征。据我们所知，以前在抗合成酶综合征患者中没有报道过视网膜血管炎。
