Beral V, Bull D, Jaffe H, Evans B, Gill N, Tillett H, Swerdlow A J
Imperial Cancer Research Fund, Cancer Epidemiology Unit, Radcliffe Infirmary, Oxford.
BMJ. 1991 Mar 16;302(6777):624-5. doi: 10.1136/bmj.302.6777.624.
To determine whether the risk of Kaposi's sarcoma in patients with AIDS is increased by sexual contact with groups from abroad with a high incidence of Kaposi's sarcoma.
Analysis of risk of Kaposi's sarcoma in patients with AIDS, according to country of origin of their sexual partners.
United Kingdom.
2830 patients with AIDS reported to the Communicable Disease Surveillance Centre and the Communicable Disease (Scotland) Unit up to March 1990, of whom 566 had Kaposi's sarcoma.
Percentage of patients with AIDS who had Kaposi's sarcoma.
537 of 2291 homosexual or bisexual men (23%) with AIDS had Kaposi's sarcoma; 10% (14/135) of the men and women who acquired HIV by heterosexual contact had Kaposi's sarcoma. None of the 316 subjects who acquired HIV through non-sexual routes had Kaposi's sarcoma. Kaposi's sarcoma was more common among homosexual men whose likely source of infection included the United States (171/551, 31%) or Africa (9/34, 26%) than among those infected in the United Kingdom (119/625, 19%) (p less than 0.05).
The data suggest that Kaposi's sarcoma is caused by a sexually transmissible agent which was introduced into the British homosexual population mainly from the United States [corrected].
确定艾滋病患者与来自卡波西肉瘤高发国家的群体发生性接触是否会增加患卡波西肉瘤的风险。
根据艾滋病患者性伴侣的原籍国分析其患卡波西肉瘤的风险。
英国。
截至1990年3月向传染病监测中心和传染病（苏格兰）部门报告的2830例艾滋病患者，其中566例患有卡波西肉瘤。
患卡波西肉瘤的艾滋病患者百分比。
2291例患有艾滋病的同性恋或双性恋男性中有537例（23%）患有卡波西肉瘤；通过异性接触感染艾滋病毒的男性和女性中有10%（14/135）患有卡波西肉瘤。通过非性途径感染艾滋病毒的316名受试者中无人患有卡波西肉瘤。卡波西肉瘤在可能的感染源包括美国（171/551，31%）或非洲（9/34，26%）的同性恋男性中比在英国感染的同性恋男性中更常见（119/625，19%）（p<0.05）。
数据表明，卡波西肉瘤是由一种主要从美国传入英国同性恋人群的性传播病原体引起的[已修正]。
