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穿孔性弹性组织变性:液氮冷冻疗法治疗及文献复习。

Elastosis perforans serpignosa: treatment with liquid nitrogen cryotherapy and review of the literature.

机构信息

Department of Dermatology and Skin Science, University of British Columbia, Vancouver, BC, Canada.

出版信息

J Cutan Med Surg. 2010 Jan-Feb;14(1):38-42. doi: 10.2310/7750.2009.08064.

Abstract

BACKGROUND

Elastosis perforans serpiginosa (EPS) is a rare skin disease in which abnormal elastic tissue fibers, other connective tissue elements, and cellular debris are expelled from the papillary dermis via transepithelial elimination. It is characterized by an eruption of small grouped hyperkeratotic papules in a serpiginous arrangement. This condition presents a therapeutic challenge as many treatments have been reported with inconsistent efficacy.

METHODS

This article reports a case of a 13-year-old male who presented to our outpatient clinic with a 1-year history of facial lesions showing multiple annular keratotic plaques with slight central atrophy.

CONCLUSION

We report a case of EPS treated successfully with liquid nitrogen cryotherapy. Liquid nitrogen cryotherapy is well tolerated, with few side effects, and can be considered in the management of EPS.

摘要

背景

弹性纤维穿孔性皮肤松懈症(EPS)是一种罕见的皮肤疾病,其特征为表皮内排出异常弹性组织纤维、其他结缔组织成分和细胞碎片。病变表现为成群小的角化过度性丘疹呈匐行性排列。由于许多治疗方法的疗效不一致,因此这种情况具有治疗挑战性。

方法

本文报告了 1 例 13 岁男性患者,其面部病变 1 年,表现为多个环形角化斑块,中央轻度萎缩。

结论

我们报告了 1 例成功用液氮冷冻疗法治疗的 EPS 病例。液氮冷冻疗法耐受性良好,副作用少,可考虑用于 EPS 的治疗。

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