Department of Dermatology, Pistoia Hospital, Pistoia, Italy.
J Cutan Med Surg. 2010 Jan-Feb;14(1):43-5. doi: 10.2310/7750.2009.08084.
The development of melanoma metastasis to the palatine tonsil is a very rare event, generally associated with advanced-stage disease and poor prognosis.
A 29-year-old man presented with a melanoma metastasis to the right palatine tonsil 6 months after the surgical excision of an ulcerated nodular melanoma (tumor thickness 1.8 mm, Clark level IV) on the left shoulder. A metastatic sentinel lymph node had been removed from the left axilla, and a subsequent complete lymph node dissection had disclosed no further metastatic lymph nodes. Although staging tests had revealed multiple visceral metastases, a palliative tonsillectomy was performed. The patient died of metastases 5 months later.
The case presentation suggests that careful examination of the head and neck should be part of the routine follow-up visit in all melanoma patients.
黑色素瘤转移至腭扁桃体是一种非常罕见的事件,通常与晚期疾病和预后不良相关。
一名 29 岁男性,在左肩部溃疡性结节性黑色素瘤(肿瘤厚度 1.8 毫米,Clark 分级 IV)切除 6 个月后,出现右侧腭扁桃体黑色素瘤转移。曾从左侧腋窝取出一个转移性前哨淋巴结,随后进行的完全淋巴结清扫术未发现其他转移性淋巴结。尽管分期检查显示有多个内脏转移,但仍进行了姑息性扁桃体切除术。患者 5 个月后死于转移。
该病例提示,所有黑色素瘤患者的常规随访都应包括对头颈部的仔细检查。