Section of Adolescent Medicine, Indiana University School of Medicine, Health Information & Translational Sciences, Indianapolis, IN 46202, USA.
Gynecol Oncol. 2010 May;117(2 Suppl):S26-31. doi: 10.1016/j.ygyno.2010.01.028. Epub 2010 Feb 2.
The quadrivalent vaccine has been shown to be safe and efficacious against HPV infection in men. It is expected, though, that male vaccination rates will remain low. Therefore this literature review examines the attitudes of parents, young men, and HCPs toward HPV vaccination and other sexually transmitted infections (STI). It appears that parents are interested in vaccinating their sons against HPV and other (STI). In addition, adolescent and adult males are interested in receipt of HPV vaccine and other vaccines for prevention of STI. Health care providers have a general preference for vaccinating females, but they indicate a willingness to recommend HPV vaccine for their male patients. This is important given the "permissive" recommendation for male HPV vaccination issued by the US Advisory Committee on Immunization Practices (ACIP). Cost effectiveness studies have shown that vaccinating males and females is less cost effective than vaccinating females alone. With low female vaccination rates, both cost effectiveness and health benefits increase. It is clear that males have poor knowledge of HPV infection, morbidity, transmission and prevention. Regardless of vaccination strategies adopted, efforts should be made to educate males about HPV and its health implications. In addition, there are more challenges to overcome before male vaccination can be successfully implemented.
四价疫苗已被证明可安全有效地预防男性 HPV 感染。然而，预计男性疫苗接种率仍将保持较低水平。因此，本文献综述考察了父母、年轻男性和 HCP 对 HPV 疫苗接种和其他性传播感染 (STI) 的态度。似乎父母有兴趣为儿子接种 HPV 和其他 (STI) 疫苗。此外，青少年和成年男性对 HPV 疫苗和其他预防 STI 的疫苗接种也感兴趣。医疗保健提供者普遍倾向于为女性接种疫苗，但他们表示愿意为男性患者推荐 HPV 疫苗。鉴于美国免疫实践咨询委员会 (ACIP) 发布了对男性 HPV 疫苗接种的“许可”建议，这一点很重要。成本效益研究表明，接种男性和女性的疫苗不如单独接种女性疫苗的成本效益高。随着女性疫苗接种率的降低，成本效益和健康益处都会增加。很明显，男性对 HPV 感染、发病率、传播和预防的了解甚少。无论采用何种疫苗接种策略，都应努力教育男性了解 HPV 及其对健康的影响。此外，在成功实施男性疫苗接种之前，还需要克服更多的挑战。
